经支气管镜微波治疗联合瘤体注射无水酒精治疗中央型肺癌疗效探讨
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[摘要] 目的 探讨经支气管镜微波治疗联合瘤体注射无水酒精治疗中央型肺癌疗效。方法 将65例中央型肺癌患者随机分为治疗组和对照组两组，对照组32例采用单纯化疗治疗；治疗组33例在此基础上经支气管镜微波联合瘤体注射无水酒精联合治疗，治疗1个月。结果与对照组相比，治疗组的KPS评分及症状明显改善情况明显优于对照组(P<0.01)；治疗组病情较对照组有明显好转(P<0.05)，而毒副反应轻微。结论经纤维支气管镜(FB)引导行微波组织凝固(MTC)联合无水酒精瘤内注射治疗中心型肺癌能有效缓解中、晚期中心型肺癌患者局部阻塞表现，减轻痛苦，提高生活质量，且毒副反应轻微。
[关键词]肺癌；高龄；外科治疗
[中图分类号] R734.2 [文献标识码]B [文章编号] 1673-9701(2011)19- 30-02
The Efficacy of Microwave Therapy Via Bronchoscopy Combined with Intratumoral Injection of Absolute Alcohol for Treatment of Central Lung Cancer
YING WeipingWANG Hui
Respiratory Department of Jinhua CityGuangfu Hospital of Zhejiang Province，Jinhua321000，China
[Abstract] ObjectiveTo explore the bronchoscope microwave treatment joint pseudo aneurysm resection without water treatment of alcohol injection central lung cancer curative effect. Methods 65 patients with central lung cancer patients were randomLy divided into two groups. The control group 32 cases，chemotherapy treatment. 33 cases in treatment group， and based on this，the bronchoscope microwave joint pseudo aneurysm resection combined treatment without water injection alcohol for 1 month. ResultsComparedwith the control group，the treatment group KPS score and the symptoms improved situation obviously better than the control group (P<0.01).The treatment group compared with the illness is improved significantly(P<0.05).But side-effect of light. Conclusion Via fiber optic bronchoscope (FB)guide line microwave organization solidification (MTC) joint anhydrous alcohol tumor therapy center within that can effectively relieve lung cancer in patients with lung cancer，later center type local clogging performance， reduce pain， improve the quality of life， and slightly adverse reaction.
[Key words] Lung cancer；Senility；Surgical treatment
肺癌是目前最常见的恶性肿瘤之一，约有3/4的肺癌为中央型。纤维支气管镜微波组织凝固技术(micro wave tissue coagulation，MTC)联合无水酒精瘤内注射 (percutaneous intratumor alcohol injection，PAI)治疗支气管内肿瘤是肺癌姑息疗法之一，可使腔内新生物缩小或消失，改善气道阻塞及阻塞性肺炎，缓解呼吸困难[1]。2007年1月～2010年9月我院在全身化疗基础上经纤维支气管镜(FB)引导行微波组织凝固(MTC) 联合无水酒精瘤内注射治疗中心型肺癌，取得较好的疗效，现报道如下。
1 资料与方法
1.1 一般资料
选择2007年1月～2010年9月我院经电子支气管镜检查行组织活检，病理检查确诊的中心型肺癌病例65例 ......
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