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间苯三酚联合地西泮在产程中应用的临床观(1)
http://www.100md.com 2011年7月15日 刘晓宁 刘岩
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     [摘要] 目的 观察间苯三酚联合地西泮在产程进展中作用。方法 选择正常初产妇,宫口开大2~3cm、伴宫颈水肿80例。随机分为间苯三酚联合地西泮组(实验组40例),待宫口开大2~3cm后给予间苯三酚40mg静脉推注,地西泮10mg静脉推注。间苯酚组(对照组40例) ,待宫口开大2~3cm后,给予间苯三酚40mg静脉推注。观察两组产妇用药后的产程变化及围产儿结局。结果 ①用药至宫口开全的时间,实验组平均为(3.2±0.31)h,对照组平均为(4.5±0.4)h,两组比较,差异有显著统计学意义(t=7.54, P<0.01)。②用药后2h的宫颈水肿消失率,实验组为97.5%,对照组为90%,两组比较,差异有统计学意义(χ2=8.04,P<0.01);用药后2h较用药前平均宫口开大,实验组(4.5±0.2)cm,对照组平均为(2.5±0.4)cm,两组比较,差异有显著统计学意义(t=7.63, P<0.01)。③ 实验组用药后30min,4例孕妇胎心率基线下降至(110~120)次/min,约60min后恢复。对照组无胎心率异常。④阴道分娩率,实验组为92.5%,对照组为95%,两组比较,差异无统计学意(χ2=0.67, P>0.05)。⑤产时羊水情况、新生儿窒息情况及新生儿体重在两组间比较,差异无统计学意义(P<0.05)。⑥两组产妇产后出血量比较,差异无统计学意义(μ=0.65, P<0.05)。结论 间苯三酚联合地西泮对促进孕妇宫口扩张,缓解宫颈水肿,加速产程进展有更明显的作用,且对母儿无明显的不良影响。

    [关键词] 间苯三酚;地西泮;子宫颈;分娩

    [中图分类号]R714.3 [文献标识码] B[文章编号]1673-9701(2011)20-69-02

    Role the Phloroglucinol Combined with Diazepan in the Childbirth process

    LIU Xiaoning LIU Yan

    Qingdao City Mother and Child Hospital, Qingdao 266011, China

    [Abstract] Objective Toexplore the role the phloroglucinol combined with diazepan in the childbirth processMethodsNormal primipara with cervical expand 2~3cm and cervical edema 80 cases were selected,and were randomly divided into two groups,phloroglucinol ally antipsychoticgroup 40 cases,were given phloroglucinol 40mg and antipsychotic 10mg in intravenous injection,phloroglucinol group 40 cases were given phloroglucinol 40mgin intravenous injection. Childbirthprocess changes and perinatal outcome were observed after administration. ResultsTime from cervix with medication to full open in phloroglucinol allyantipsychotic group was(3.2±0.31)h,(4.5±0.4)hinphloroglucinol group,thedifference was significant (t=7.54, P<0.0 1). Cervical edema disappearance rate in 2 h after treatment was 97.5% in phloroglucinol ally antipsychotic group ......

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