微量元素硒对老年性白内障的影响(1)
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[摘要] 目的 探讨微量元素硒与老年性白内障的关系。方法将实验分为实验组与对照组分别测定硒含量，观察硒对老年性白内障的影响。结果含硒量缺乏与有无老年性白内障有显著性差异(P<0.01)，但含硒量过多与有无老年性白内障并无明显差异，提示了老年性白内障与体内微量元素硒有密切的关系。结论 老年性白内障的预防和治疗中应重视摄硒问题，有必要调适摄硒量。
[关键词] 老年人；白内障；微量元素硒；抗氧化作用
[中图分类号] R776.1[文献标识码]B[文章编号] 1673-9701(2011)27- 41-02
The Influence of Microelement Se on the Senile Cataract
JIANG Zhenger1JIN Meiying2
Yanbian University Foundation Medical CollegeYanji 133002, China；2. Yanji City Traditional Chinese Medicine Hospital，Yanji 133000，China
[Abstract] ObjectiveTo discussthe relationship of microelement Se to the senile cataract. Methods The experimental was divided into experimental group and control group，separately admeasuremented content of microelement Se，to observe the influence of microelement Se to the senile cataract. Results There was significant difference of the lack of the microelement Se to the senile cataract(P<0.01)，but there was no significant difference of too much the microelement Se with the senile cataract. And there was intimate relationship of the senile cataract to the internal content of microelement Se. Conclusion In the preventing and treating the senile cataract，we must pay attention to microelement Se，but also be necessary to adjust the absorbed the quantity of the microelement Se.
[Key words] Senile；Cataract；Microelement Se(Se)；Antioxidation
微量元素硒是眼组织中必不可少的元素[1]，眼睛是人体含硒较高的组织，硒作为谷胱甘肽过氧化酶(GSH-Px)的组成成分，含硒的GSH-Px具有抗氧化作用，催化还原型谷胱甘肽转变为氧化型谷胱甘肽，保护生物膜结构和功能。老年性白内障是晶体内硒含量降低，若长期缺硒使GSH-Px减少，晶状体受到过氧化氢的损害，引起晶体蛋白质降解，蛋白质脂膜氧化，膜通透性增加，细胞膜破裂，晶体混浊形成白内障[2,3]。过量的硒也能导致白内障，因硒具有强氧化-还原性，它与分子态氧化作用生成活性氧，能触发晶体的脂质过氧化反应，在晶状体中形成不溶性高分子聚集体，导致晶状体混浊形成白内障[4,5]。为了探讨硒影响老年性白内障的相关因素，分两组进行硒含量的测定，现报道如下。
1对象与方法
1.1对象 ......
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