二甲硅油在胶囊内镜检查中的应用(1)
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[摘要] 目的 探讨二甲硅油在胶囊内镜检查中对图像清晰度及小肠通过时间的影响。方法 选择在我院接受胶囊内镜检查的90例健康体检者,随机分为二甲硅油(50mL,浓度为0.5%)组、二甲硅油(100mL,浓度为0.5%)组和对照组各30例,观察各组图像的气泡量、观察效果,记录胶囊内镜在小肠的通过时间,对其结果进行统计学分析。 结果 二甲硅油(100mL)组小肠肠道内的气泡较少、图像清晰度较好,三组比较差异有统计学意义(P<0.05);三组胶囊小肠通过时间分别为(222.8±60.2)min、(220.8±60.2)min和(224.5±53.9)min,组间比较差异无统计学意义(P>0.05)。结论 二甲硅油能够提高胶囊内镜检查时小肠黏膜观察的清晰度,并与其使用剂量相关,对小肠通过时间无影响。
[关键词] 二甲硅油;胶囊内镜
[中图分类号] R574.5 [文献标识码] B [文章编号] 1673-9701(2011)27-57-02
Application Value of Dimethicone Powder in Capsule Endoscopy
ZHANG YuJIN JianjunZHAO ShuangqinZHANG ShitongZHANG YingjianBAI YanliZHENG Yufeng
Department of Gastroenterology, the First Affiliated Hospital of Henan Science and Technology University, Luoyang 471003 China
[Abstract] Objective To study the vision clarity of dimethicone powder in capsule endoscopy and compare the time of capsule in the small intestine. Methods Ninty health people were randomly divided into group 1 of dimethicone powder(50% dimethicone 50 mL),group 2 of dimethicone powder(50% dimethicone 100mL) and control group. The image qualities of capsule endoscopy of three groups were graded according to air bubble size, and the times of capsule in the small intestine were compared. Results Comparing three groups, the bubbles of the bowel in the study groups were less, and the pictures became sharper(P<0.05);The capsule transit times of the three groups have no significant difference existed(P>0.05). Conclusion The application of dimethicone administration before capsule endoscopy improves the visualization of the intestinal mucosa, and the cleaning level is relevant to the dose of dimethicone powder, the small bowel transit time is unaffected.
[Key words] Dimethicone powder;Capsule endoscopy
胶囊内镜自2001年问世以来,已成为许多小肠疾病的首选诊断方法,具有无痛苦、无创伤、无交叉感染等优点,可以直接地观察到小肠黏膜病变,但胶囊内镜的诊断性能并不完全尽如人意,除了仪器本身的局限性外,食物残渣、胆汁、气泡等都制约胶囊内镜图像的清晰度。近年来,已总结出多种有效的清肠方法以避免食物残渣、胆汁等的影响,但小肠中过多气泡的存在仍影响着图像清晰度,制约检出率的提高。研究表明,二甲硅油作为一种祛泡剂被证实在胃镜检查中能有效减少气泡,提高图像清晰度[1]。本研究将二甲硅油应用于胶囊内镜检查,旨在探讨其对胶囊内镜图像质量和胶囊通过时间的影响。
1资料与方法
1.1临床资料
2009年11月~2011年5月在我院接受胶囊内镜检查者共90例 ......
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