布地奈德混悬液联合可必特雾化吸入治疗儿童哮喘发作的疗效观察(1)
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[摘要]目的 探讨布地奈德混悬液联合可必特雾化吸入治疗儿童哮喘的疗效。方法 78例发作期儿童哮喘患儿随机分为观察组和对照组各39例，对照组行常规药物治疗，观察组在对照组的基础上予布地奈德混悬液联合可必特雾化吸入治疗。观察比较两组治疗前后的临床症状、体征消失时间、住院时间及不良反应情况。结果 观察组患儿咳嗽、喘息、呼吸困难及肺部哮鸣音消失时间明显短于对照组(P<0.05)。观察组患儿治疗后的有效率高于对照组(P<0.05)。两组治疗期间未见明显不良反应，观察组的住院时间明显短于对照组(P<0.05)。结论 布地奈德混悬液联合可必特雾化吸入治疗儿童哮喘发作疗效确切，未见明显不良反应，值得推广和应用。
[关键词] 哮喘；发作；布地奈德混悬液； 可必特；雾化吸入
[中图分类号] R562.2+5 [文献标识码] B [文章编号] 1673-9701(2011)32-64-02
Efficacy of Budesonide Suspension Combined with Pitt by Inhalation in Treatment of Children with Asthma Attack
BAI Li1 GAO Yu 2 WANG Weilie1
1.Daqing Oil field General Hospital , Daqing 163001，China; 2. Fifth Affiliated Hospital of Harbin Medical University , Daqing 163001，China
[Abstract] Objective To investigate the combined budesonide suspension for inhalation therapy may be necessary especially children with asthma treatment. Methods All 78 cases of exacerbation of asthma were randomly divided into two groups with 39 cases in each , patients in control group underwent conventional drug treatment, observation group were based on the joint to the suspension of budesonide can Pitt inhalation therapy. Before and after treatment were observed and compared the clinical symptoms and signs disappeared more time and duration of stay, and adverse reactions. Results The children with cough, wheezing, difficulty breathing and lung wheeze disappeared significantly shorter than the control group (P<0.05). Observation group after treatment in children with efficiency higher (P<0.05) . Two groups no significant adverse reactions during treatment occurred in the observation group of hospital stay was significantly shorter than the control group (P<0.05) . Conclusion Budesonide suspension will be special joint treatment of children with asthma inhalation of curative effect, no significant adverse reactions, should be promoted and applied.
[Key words] Asthma; Attack; Suspension; Pitt; Inhalation
哮喘是儿童时期常见的反复发作的慢性疾病，近年来日趋小龄化，严重地影响患儿的身心健康，故治疗药物的应用对于哮喘的防治至关重要[1]。2009年1月～2011年1月我们应用布地奈德混悬液联合可必特雾化吸入治疗儿童哮喘39例，取得了较好的疗效。现报道如下。
1 资料与方法
1.1 临床资料
选择2009年1月～2011年1月我院收治的78例发作期儿童哮喘患儿作为观察对象，符合中华医学会儿科学会呼吸学组《儿童支气管哮喘诊断与防治指南》的诊断标准[2]。其中男40例，女38例，男女之比1.05︰1.年龄8个月～12岁，平均(4.7±1 ......
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