肾病综合征中血小板参数测定的临床意义(1)
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[摘要] 目的 探讨肾病综合征患者中进行血小板参数测定的临床意义。方法 收集2003年5月～2011年3月来我院进行治疗的肾病综合征患者55例进行研究，并作为观察组，选取同期来我院进行健康体检的正常人51例作为对照组，对其PLT、MPV及PDW等血小板参数进行检测。对两组患者的检测结果进行比较。结果 与对照组比较，观察组治疗前的PLT较高，但是两组间无显著性差异；MPV及PDW均明显较高，有显著性差异(P<0.05)；观察组治疗后的PLT、MPV、PDW等血小板参数无显著性差异。与观察组治疗前比较，治疗后PLT降低，差异无统计学意义；MPV及PDW均明显降低，治疗前后比较差异有显著性(P<0.05)。结论 对肾病综合征患者进行血小板的检测有非常重要的作用，有利于病情的分析，对患者血栓形成的临床诊断具有非常重要的临床意义。
[关键词] 肾病综合征；血小板；测定
[中图分类号] R692 [文献标识码] B [文章编号] 1673-9701(2011)33-69-02
Nephrotic Syndrome in the Clinical Significance of Platelet Parameters Determined
CHEN Jinjin
Department of Outpatient Laboratory，Huzhou First People's Hospital in Zhejiang Province，Huzhou 313000，China
[Abstract] Objective To investigate patients with nephrotic syndrome in the clinical significance of platelet parameters measured. Methods All 51 patients with nephrotic syndrome in our hospital from May 2003 to March 2011 were treated as the observation group，selected the same year to the hospital for physical examination of the normal 51 cases as control group，examined their PLT，MPV and PDW. We compared the results of the two groups. Results Compared with control group，PLT in pre-treatment observation group was higher，but no significant difference between the two groups；MPV and PDW were significantly higher，there were significant differences(P<0.05)；PLT，MPV and PDW in observation group after treatment were no significantly difference. Compared with observation group before treatment，PLT in observation group after treatment decreased，the difference was no statistically significant；MPV and PDW were significantly lower after treatment and the difference was significant(P<0.05). Conclusion There has a very important role of patients with the nephrotic syndrome with platelet testing. It can help the disease analysis，the clinical diagnosis of thrombosis in patients with very important clinical significance.
[Key words] Nephrotic syndrome；Platelets；Determination
肾病综合征往往具有病情复杂的特点，主要是因为此类患者常处于高凝状态，并常常形成血栓，高凝状态的形成是由很多方面共同作用导致的，但是其中一个重要的因素就是患者血小板功能发生改变[1]。笔者对2003年5月～2011年3月来我院进行治疗的肾病综合征患者51例进行研究 ......
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