[摘要] 目的 评价大剂量MTX联合米非司酮治疗异位妊娠的疗效。方法 100例异位妊娠患者，随机分成观察组和对照组。对照组采用大剂量MTX治疗；观察组采用大剂量MTX加用米非司酮治疗。 结果 观察组总有效率92.00%高于对照组78.00%，具有统计学意义(P < 0.05)。两组均未发现明显不良反应。 结论 大剂量MTX联合米非司酮治疗异位妊娠患者疗效可靠。

    [关键词] 甲氨蝶呤；大剂量；米非司酮；异位妊娠

    [中图分类号] R714.22[文献标识码] B[文章编号] 1673-9701(2012)10-0125-02

    Evaluation of efficacy that high-dose MTX and mifepristone treatment of 50 cases of ectopic pregnancy

    ZHU Lanyu

    Department of Obstetrics and Gynecology， MCH of Heyuan in Guangdong Province，Heyuan 517000, China

    [Abstract] Objective To evaluation of efficacy about high-dose MTX and mifepristone treatment of ectopic pregnancy. Methods 100 cases of ectopic pregnancy divided into the observation group and the control group. The control group：high-dose MTX treatment. The observation group：high-dose MTX and mifepristone treatment. Results The total effective rate of the observation group is 92.00% higher than 78.00% of the control group, with statistical significance (P < 0.05). Two groups no obvious adverse reactions. Conclusion It is a reliable curative effect that high-dose MTX and mifepristone treatment of ectopic pregnancy. ......