参麦注射液治疗急性非ST段抬高型心肌梗死及对组织因子途径抑制物—2的影响(1)
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[摘要] 目的 探讨参麦注射液对急性非ST段抬高型心肌梗死治疗疗效并了解其机制。 方法 选非ST段抬高型心肌梗死患者170例随机分观察组及对照组各85例，对照组常规西药治疗，观察组在对照组的基础上应用参麦注射液。观察临床症状及心电图缓解情况，并检测治疗前后患者血浆组织因子途径抑制物2的浓度。 结果 临床治疗效果观察组总有效率90.59%，心电图改善总有效率91.67%高于对照组的76.47%、77.64%。两组治疗前组织因子途径抑制物—2水平无显著性差异(P > 0.05)；治疗以后观察组(7.79±1.112)ng/mL低于对照组的(8.86±1.29)ng/mL，差值为(2.24±0.78)ng/mL高于对照组的(1.14±0.60)ng/mL(P < 0.05)。 结论 参麦注射液可有效提高急性非ST段抬高型心肌梗死治疗效果及心电图改善，参麦注射液对急性非ST段抬高心肌梗死的治疗作用可能与组织因子途径抑制物—2水平变化相关。
[关键词] 参麦注射液；急性非ST段抬高型心肌梗死；组织因子途径抑制物—2
[中图分类号] R286 [文献标识码] B [文章编号] 1673—9701(2012)26—0058—03
The Efficacy of Shenmai injection on non—ST elevation myocardial infarction and its effect on tissue factor pathway inhibitor—2
WU Lianpin1 CHEN Gang2 GAO Xuezhong2 LIU Gang2 Aili·Maihemuti2
1.Department of Cardiology， the Second Affiliated Hospital of Wenzhou Medical College， Wenzhou 325000， China； 2.Department of Cardiology， the Aksu First People’s Hospital in Xinjiang Uygur Autonomous Region， Aksu 843000， China
[Abstract] Objective To study clinical effects of Shenmai injection on non—ST elevation myocardial infarction(NSTEMI) and understand its mechanism. Methods All of 170 cases with NSTEMI were divided into treatment group (85 cases) and control group (85 cases). Treatment group was conventional western medicine plus Shenmai injection. Otherwise， the control group was conventional western medicine. Observed symptoms and ECG remission situation and detected the plasmatissue factor pathway inhibitor—2(PTFI—2) concentration before and after treatment. Results In treatment group， total effective rate of clinical treatment effect was 90 ......
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