培菲康、茵栀黄联合光疗治疗新生儿高胆红素血症的疗效观察(1)
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[摘要] 目的 观察培菲康、茵栀黄联合光疗治疗新生儿高胆红素血症的临床疗效。 方法 将60例临床确诊的新生儿高胆红素血症患儿随机分成治疗组(培菲康、茵栀黄联合光疗治疗)和对照组(光疗)各30例，比较两组的疗效以及两组治疗前后胆红素值的变化。 结果 治疗组总有效率为90.0%，对照组总有效率为70.0%，差异有统计学意义(χ2=6.235，P < 0.05)。治疗前两组胆红素值差异无统计学意义(t = 0.512，P > 0.05)；治疗后两组的胆红素值均明显降低，且治疗组较对照组降低更显著，差异有统计学意义(t = 12.327，P < 0.01)。 结论 培菲康、茵栀黄联合光疗治疗新生儿高胆红素血症疗效确切，值得推广和应用。
[关键词] 新生儿高胆红素血症；培菲康；茵栀黄；光疗
[中图分类号] R722.17 [文献标识码] B [文章编号] 1673—9701(2012)26—0068—02
Clinical observation of Bifico， Yinzhihuang plus phototherapy in treatment of neonatal hyperbilirubinemia
ZHANG Wenying
Department of Neonatology， Suzhou Municipal Hospital， Suzhou 215002， China
[Abstract] Objective To explore clinical efficacy of Bifico， Yinzhihuang combined with phototherapy treatment of neonatal hyperbilirubinemia. Methods Sixty cases of clinically diagnosed children with neonatal hyperbilirubinemia were randomly divided into treatment group (Bifico， Yinzhihuang， phototherapy treatment) and control group (phototherapy) with 30 cases in each group， and compared the efficacy and bilirubin before and after treatment. Results The total effective rate of the treatment group was 90.0%， and that of the control group was 70.0%， there existed significant difference (χ2=6.235， P < 0.05). Before treatment， bilirubin had no significant difference (t = 0.512， P > 0.05). After treatment， the bilirubin values of the two groups were significantly lower， and the treatment group reduced more significantly compared with the control group， and the difference was significant (t = 12.327， P < 0.01). Conclusion Bifico， Yinzhihuang plus phototherapy in treatment of neonatal hyperbilirubinemia has definite efficacy and worth of extensive promotion and application ......
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