糖皮质激素在小儿急性上呼吸道感染中应用的疗效及不良反应(1)
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[摘要] 目的 分析糖皮质激素在小儿急性上呼吸道感染中应用的疗效及不良反应。 方法 选择2009年8月～2010年8月我院收治的80例急性上呼吸道感染患儿，随机分为观察组与对照组各40例，观察组患儿接受糖皮质激素治疗，对照组患儿接受其他药物治疗，依照病情采取抗病毒药物或抗菌药物进行治疗，观察并分析患儿的退热时间、用药后的不良反应和并发症。 结果 观察组患儿与对照组相比表面体温下降，症状得到有效缓解(P < 0.05)，但不良反应严重，糖皮质激素延长了患儿的病程且使并发症增多，两组比较差异有统计学意义(P < 0.05)。 结论 使用糖皮质激素治疗由急性上呼吸道感染引起的小儿发热弊大于利。
[关键词] 糖皮质激素；急性上呼吸道感染；儿童
[中图分类号] R725.6 [文献标识码] B [文章编号] 1673—9701(2012)26—0128—02
The efficacy and adverse reactions of corticosteroids in treatment of children acute upper respiratory tract infection
LIU Hui
Department of Pharmacy， Maternity and Child Care Center of Heyuan City in Guangdong Province， Heyuan 517000， China
[Abstract] Objective To analyze the efficacy and adverse reactions of corticosteroids in treatment of children acute upper respiratory tract infection. Methods Eighty cases of children with acute upper respiratory tract infection in our hospital from August 2009 to August 2010 were choosed and ramdonly divided into observation group and control group with 40 cases in each. Patients of the observation group received corticosteroids therapy， and patients of the control group received other medication therapy， and fever clearance time， adverse drug reactions and complications of two groups were observed and analyzed. Results Compared with the control group， the surface temperature of the observation group declined， and symptoms were effectively alleviated (P < 0.05) but adverse reactions were more serious， and glucocorticoids prolonged course of children and the complications increased (P < 0.05). Conclusion Treatment of children fever caused by acute upper respiratory tract infection with glucocorticoids has more harm than good.
[Key words] Corticosteroids； Acute upper respiratory tract infection； Children ......
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