维持性腹膜透析剂量与ESRD患者的饮食蛋白摄入总量、残肾功能、血尿素浓度关系探讨(1)
[摘要] 目的 探讨维持性腹膜透析剂量与ESRD患者的饮食蛋白摄入总量、残肾功能、血尿素浓度关系。 方法 回顾性分析我院ESRD患者的临床资料。通过Matlab 6.5软件作饮食蛋白摄入总量、残肾功能、血尿素浓度与维持性腹膜透析剂量的关系曲线。 结果 患者每天通过腹透液和尿液丢失的蛋白质氮平均为(0.94±0.48)g/d，氨基酸氮及其他形式的非尿素氮丢失分别为(0.51±0.12)g/d及(31.4±5.3)mg/(kg·d)，与透析剂量的关系曲线显示，饮食蛋白摄入总量越多，残肾功能越差，血尿素浓度越高，则需要的透析剂量越大。 结论 在保证患者不会发生营养不良的前提下，适当控制饮食蛋白和水的摄入，保护残肾功能，维持适当的血尿素浓度，可以有效减少透析剂量，节约透析费用。
[关键词] 维持性腹膜透析；终末期肾病；蛋白摄入总量；残肾功能；血尿素浓度
Investigation on the relation between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake，residual renal function、blood urea level in ESRD Patients
, 百拇医药
SHAN Yisheng1，2 XU Feifei1 SUN Mei1 LIN Fan1
1.Internal Medicine， the First Affiliated Hospital of Wenzhou Medical University， Wenzhou 325000， China；2.Internal Medicine， Wenzhou Kangning Hospital， Wenzhou 325000， China
[Abstract] Objective To investigate the relation between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake，residual renal function，blood urea level in ESRD Patients. Methods The clinical data of ESRD patients in our department were analyzed retrospectively. The relationship curve between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake， residual renal function， blood urea concentration were established through Matlab 6.5 software. Results Every day protein nitrogen average through the drain fluid loss and urine of patient was(0.94±0.48) g/d， and other forms of amino acid nitrogen of urea nitrogen loss， respectively was(0.51±0.12)g/d，(31.4±5.3)mg/(kg·d). the relationship with dialysis dose curve showed that the more amount of dietary protein intake， the greater the dialysis dose. The poor residual renal function， the greater the dialysis dose. The higher the concentration of blood urea， the greater the dialysis dose. Conclusion On the premise of guarantee patient’s nutrition， appropriate control the intake of dietary protein and water， protection of residual renal function， maintain proper blood urea concentration， can effectively reduce dialysis dose， cut down the cost of dialysis.
, 百拇医药
[Key words] Maintenance peritoneum dialysis； End stage renal disease(ESRD)； The total quantity of dietary protein intake； Residual renal function； Blood urea level
随着人们生活方式的改变和高血压、糖尿病发病率的升高，终末期肾脏病(End stage renal disease，ESRD)的发病率越来越多。腹膜透析是ESRD患者的有效的治疗方式，而且是透析患者的首选治疗方式。但目前腹膜透析的发展没有达到应有的水平，其原因之一就是透析方案的不合理和透析不充分，使腹膜透析疗效下降，降低了生活质量、生存率[1]。目前，维持性腹膜透析剂量相关研究较少，而且不明确。本研究旨在探讨维持性腹膜透析剂量与终末期肾病患者的饮食蛋白摄入总量、残肾功能、血尿素浓度关系，现报道如下。, 百拇医药(单亦升等)
[关键词] 维持性腹膜透析；终末期肾病；蛋白摄入总量；残肾功能；血尿素浓度
Investigation on the relation between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake，residual renal function、blood urea level in ESRD Patients
, 百拇医药
SHAN Yisheng1，2 XU Feifei1 SUN Mei1 LIN Fan1
1.Internal Medicine， the First Affiliated Hospital of Wenzhou Medical University， Wenzhou 325000， China；2.Internal Medicine， Wenzhou Kangning Hospital， Wenzhou 325000， China
[Abstract] Objective To investigate the relation between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake，residual renal function，blood urea level in ESRD Patients. Methods The clinical data of ESRD patients in our department were analyzed retrospectively. The relationship curve between the dosage of maintenance peritoneum dialysis and the total quantity of dietary protein intake， residual renal function， blood urea concentration were established through Matlab 6.5 software. Results Every day protein nitrogen average through the drain fluid loss and urine of patient was(0.94±0.48) g/d， and other forms of amino acid nitrogen of urea nitrogen loss， respectively was(0.51±0.12)g/d，(31.4±5.3)mg/(kg·d). the relationship with dialysis dose curve showed that the more amount of dietary protein intake， the greater the dialysis dose. The poor residual renal function， the greater the dialysis dose. The higher the concentration of blood urea， the greater the dialysis dose. Conclusion On the premise of guarantee patient’s nutrition， appropriate control the intake of dietary protein and water， protection of residual renal function， maintain proper blood urea concentration， can effectively reduce dialysis dose， cut down the cost of dialysis.
, 百拇医药
[Key words] Maintenance peritoneum dialysis； End stage renal disease(ESRD)； The total quantity of dietary protein intake； Residual renal function； Blood urea level
随着人们生活方式的改变和高血压、糖尿病发病率的升高，终末期肾脏病(End stage renal disease，ESRD)的发病率越来越多。腹膜透析是ESRD患者的有效的治疗方式，而且是透析患者的首选治疗方式。但目前腹膜透析的发展没有达到应有的水平，其原因之一就是透析方案的不合理和透析不充分，使腹膜透析疗效下降，降低了生活质量、生存率[1]。目前，维持性腹膜透析剂量相关研究较少，而且不明确。本研究旨在探讨维持性腹膜透析剂量与终末期肾病患者的饮食蛋白摄入总量、残肾功能、血尿素浓度关系，现报道如下。, 百拇医药(单亦升等)