[摘要] 目的 探讨过敏性结膜炎患者TGF-β1和IL-17的表达水平。 方法 对我院治疗的过敏性结膜炎患者和健康人群的TGF-β1和IL-17的表达水平进行检测，探讨在各型过敏性结膜炎患者中的表达强度。 结果 过敏性结膜炎患者TGF-β1和IL-17水平高于健康人群，差异有统计学意义(P<0.01)，过敏性结膜炎四个临床亚型中TGF-β1和IL-17的表达水平不一，以春季角结膜炎表达水平最高，其次为常年性过敏性结膜炎和季节性过敏性结膜炎，特应性角结膜炎表达水平最低，但四个临床亚型组间比较差异无统计学意义(P>0.05)。 结论 过敏性结膜炎患者TGF-β1和IL-17 表达水平高于正常健康人群。TGF-β1和IL-17在各型过敏性结膜炎患者中表达强度不同，在春季角结膜炎表达水平明显高于其他类型。

    [关键词] TGF-β1；IL-17；过敏性结膜炎

    [中图分类号] R276.7 [文献标识码] B [文章编号] 1673-9701(2015)11-0069-03

    [Abstract] Objective To investigate the expression level of transforming growth factor β1 (TGF-β1) and interleukin 17 (IL-17) in patients with allergic conjunctivitis. Methods TGF-β1 and IL-17 expression levels in allergic conjunctivitis patients hospitalized in the author’s hospital and a healthy population were detected to explore the expression level in all types of patients with allergic conjunctivitis. Results TGF-β1 and IL-17 levels were significantly higher in patients with allergic conjunctivitis than in healthy population (P<0.01). Among the four clinical subtypes of allergic conjunctivitis ......