[摘要] 目的 探讨急性胰腺炎凝血功能变化及临床意义。 方法 回顾性分析在我院进行治疗的急性胰腺炎患者80例的临床资料，根据患者病情分为轻症组46例、重症组34例。入院后检测凝血功能相关指标，并分析其与APACHEⅡ评分的相关性。 结果 轻症组PT、APTT、FIB、D-D水平与对照组比较差异无统计学意义(P>0.05)。重症组PT、APTT、FIB、D-D水平均显著高于对照组和轻症组(P<0.01)。MODS组患者凝血功能指标均显著高于MODS组(P<0.05或P<0.01)。FIB和D-D与重症患者APACHEⅡ评分呈正相关(r=0.78，0.82，P<0.01)。 结论 轻症胰腺炎患者凝血功能基本正常，而重症胰腺炎患者出现凝血功能障碍，FIB和D-D与患者病情指标APACHEⅡ具有相关性。

    [关键词] 急性胰腺炎；凝血功能；凝血酶原时间

    [中图分类号] R657.51 [文献标识码] A [文章编号] 1673-9701(2015)21-0021-03

    [Abstract] Objective To discuss significance and change of coagulation function in patients with acute pancreatitis. Methods Clinical data of 80 cases with acute pancreatitis were analyzed. 46 cases were mild acute pancreatitis as MAP group. 34 cases were severe acute pancreatitis as SAP group. Coagulation function index were detected and association between coagulation function index and APACHEⅡ. Results Levels of PT ......