当归注射液联合丹参注射液封穴疗法治疗牛皮癣的疗效分析(1)
[摘要] 目的 探讨当归注射液和丹参注射液封穴疗法治疗牛皮癣的临床疗效。 方法 选取84例牛皮癣患者作为研究对象，随机分为对照组和观察组，每组42例。对照组给予窄谱中波紫外线照射疗法进行治疗，观察组给予当归注射液和丹参注射液封穴疗法。比较分析两组患者的治疗效果及复发和不良反应情况。 结果 观察组的总有效率为90.48%，复发率为2.38%，不良反应发生率为0；对照组分别为71.43%、14.29%、9.52%。观察组的总有效率高于对照，复发率和不良反应发生率均低于对照组，差异具有统计学意义(P<0.05)。 结论 应用当归注射液和丹参注射液封穴疗法治疗牛皮癣效果显著，可有效减少复发以及不良反应的发生，值得临床推广应用。
[关键词] 当归注射液；丹参注射液；封穴疗法；牛皮癣
[中图分类号] R246.7 [文献标识码] B [文章编号] 1673-9701(2015)26-0122-03
Analysis on the effect of using Angelica injection and Danshen injection in treatment of psoriasis
LIU Zhangping
Zibo Municipal Authority Hospital in Shandong Province，Zibo 255001，China
[Abstract] Objective To explore the clinical effect of using injection of Angelica injection and Danshen injection in treatment of psoriasis. Methods A total of 84 cases of psoriasis patients were randomly divided into control group and observation group， 42 cases in each group. The control group was treated with narrow spectrum midwave ultraviolet radiation therapy treatment， the observation group was treated with Angelica injection and Danshen injection point to seal the therapy. The treatment effect and the incidence of adverse reactions were compared. Results The total effective rate of the observation group was 90.48%， the recurrence rate was 2.38%， the adverse reaction rate was 0%， and the control group was 71.43%， 14.29%， 9.52%， respectively. The total effective rate of the observation group was higher than that of the control group， the recurrence rate and adverse reaction rate were lower than that of the control group (P<0.05). Conclusion The effect of Angelica injection and Danshen injection in treatment of psoriasis is remarkable， can effectively reduce the recurrence and the occurrence of adverse reactions， it is worthy of clinical application.
[Key words] Angelica injection； Danshen injection； Acupoint therapy； Psoriasis
牛皮癣是临床上最常见的一种炎症性皮肤病，又称银屑病，具有较高发病率，其特点为根治较难、反复发作[1-4]。若不及时对牛皮癣患者采取治疗措施，则会对其工作以及日常生活造成严重影响。本研究中应用当归注射液和丹参注射液封穴疗法对牛皮癣患者进行治疗，取得了较为满意的效果，现报道如下。
1 资料与方法
1.1一般资料
选取2013年6月～2014年6月在我院接受治疗的84例牛皮癣患者作为研究对象，并按照随机分配的原则将其分为对照组和观察组，每组42例。对照组中男23例，女19例；年龄19～64岁，平均(41.6±1.5)岁；病程1～12年，平均(5.84±1.27)年。观察组中男22例，女20例；年龄19～63岁，平均(41.2±1.2)岁；病程1～11年，平均(5.46±1.31)年。两组患者在性别、年龄、病程等一般资料比较差异均无统计学意义(P>0.05)，具有可比性。
1.2诊断标准[3]
①牛皮癣起病缓慢，且易复发，具有明显的季节性，一般为冬季较为严重；②好发于四肢伸侧与头皮，其中以肘关节最为常见，常发展为全身；③患病初期为炎性红色皮疹，一般为针尖至绿豆般大小的皮肤损伤，常呈现点滴状分布，且增大速度较快，表面有银白色的多层鳞屑覆盖，形状如云母。剥离鳞屑后，会出现薄膜及筛状出血现象，将基底浸润。陈旧皮疹会呈现盘状、钱币状或者地图状；④少部分患者会发生指甲病变，轻者为指甲呈点状凹陷，重者为指甲光泽消失，甲板增厚。或者发生阴部、口腔黏膜，头皮发病者会产生束状毛发；⑤经检查发现患者的表皮过度角化或者角化不全。角层内会堆积有中性多形核白细胞，且棘层变厚。表皮突会发生规则性向下延伸，呈现棒状真皮乳头水肿，乳头内的血管扩张，炎性细胞对血管周围进行侵润[5]。, 百拇医药(刘章萍)
[关键词] 当归注射液；丹参注射液；封穴疗法；牛皮癣
[中图分类号] R246.7 [文献标识码] B [文章编号] 1673-9701(2015)26-0122-03
Analysis on the effect of using Angelica injection and Danshen injection in treatment of psoriasis
LIU Zhangping
Zibo Municipal Authority Hospital in Shandong Province，Zibo 255001，China
[Abstract] Objective To explore the clinical effect of using injection of Angelica injection and Danshen injection in treatment of psoriasis. Methods A total of 84 cases of psoriasis patients were randomly divided into control group and observation group， 42 cases in each group. The control group was treated with narrow spectrum midwave ultraviolet radiation therapy treatment， the observation group was treated with Angelica injection and Danshen injection point to seal the therapy. The treatment effect and the incidence of adverse reactions were compared. Results The total effective rate of the observation group was 90.48%， the recurrence rate was 2.38%， the adverse reaction rate was 0%， and the control group was 71.43%， 14.29%， 9.52%， respectively. The total effective rate of the observation group was higher than that of the control group， the recurrence rate and adverse reaction rate were lower than that of the control group (P<0.05). Conclusion The effect of Angelica injection and Danshen injection in treatment of psoriasis is remarkable， can effectively reduce the recurrence and the occurrence of adverse reactions， it is worthy of clinical application.
[Key words] Angelica injection； Danshen injection； Acupoint therapy； Psoriasis
牛皮癣是临床上最常见的一种炎症性皮肤病，又称银屑病，具有较高发病率，其特点为根治较难、反复发作[1-4]。若不及时对牛皮癣患者采取治疗措施，则会对其工作以及日常生活造成严重影响。本研究中应用当归注射液和丹参注射液封穴疗法对牛皮癣患者进行治疗，取得了较为满意的效果，现报道如下。
1 资料与方法
1.1一般资料
选取2013年6月～2014年6月在我院接受治疗的84例牛皮癣患者作为研究对象，并按照随机分配的原则将其分为对照组和观察组，每组42例。对照组中男23例，女19例；年龄19～64岁，平均(41.6±1.5)岁；病程1～12年，平均(5.84±1.27)年。观察组中男22例，女20例；年龄19～63岁，平均(41.2±1.2)岁；病程1～11年，平均(5.46±1.31)年。两组患者在性别、年龄、病程等一般资料比较差异均无统计学意义(P>0.05)，具有可比性。
1.2诊断标准[3]
①牛皮癣起病缓慢，且易复发，具有明显的季节性，一般为冬季较为严重；②好发于四肢伸侧与头皮，其中以肘关节最为常见，常发展为全身；③患病初期为炎性红色皮疹，一般为针尖至绿豆般大小的皮肤损伤，常呈现点滴状分布，且增大速度较快，表面有银白色的多层鳞屑覆盖，形状如云母。剥离鳞屑后，会出现薄膜及筛状出血现象，将基底浸润。陈旧皮疹会呈现盘状、钱币状或者地图状；④少部分患者会发生指甲病变，轻者为指甲呈点状凹陷，重者为指甲光泽消失，甲板增厚。或者发生阴部、口腔黏膜，头皮发病者会产生束状毛发；⑤经检查发现患者的表皮过度角化或者角化不全。角层内会堆积有中性多形核白细胞，且棘层变厚。表皮突会发生规则性向下延伸，呈现棒状真皮乳头水肿，乳头内的血管扩张，炎性细胞对血管周围进行侵润[5]。, 百拇医药(刘章萍)