黄彩秀 吴红娟 赵宇燕 李锦燕

    温州医科大学附属第二医院育英儿童医院，浙江温州325027

    生理盐水冲洗输液管残留头孢哌酮钠舒巴坦钠的影响因素

    黄彩秀吴红娟赵宇燕李锦燕▲

    温州医科大学附属第二医院育英儿童医院，浙江温州325027

    目的研究静脉输液莫菲氏滴壶液面高度、排空次数及管路冲洗滴速对0.9%生理盐水冲管效果的影响。方法采用紫外分光光度计测定配制系列浓度头孢哌酮钠舒巴坦钠的吸光度，制作标准曲线。根据次甲基蓝的不同莫菲氏滴壶内液面高度、排空次数及不同滴速3个影响因素设计分组方案，采用0.9%生理盐水冲洗，体积间隔2.0 mL，莫菲氏滴壶采样检测次甲基蓝颜色残留。结果莫菲氏滴壶1/3液面高度和2/3液面高度头孢哌酮钠舒巴坦钠，滴速50 D/min冲尽需0.9%生理盐水分别为20 mL和22 mL；滴速50 D/min和20 D/min冲管2/3液面高度头孢哌酮钠舒巴坦钠，莫菲氏滴壶采样冲尽分别需22 mL和18 mL；0.9%生理盐水以滴速20 D/min冲尽1/3液面莫菲氏滴壶高度头孢哌酮钠舒巴坦钠，无排空和1次排空法分别需14 mL和10 mL。结论莫菲氏滴壶原液液面高度、排空次数与滴速是影响生理盐水对头孢哌酮钠舒巴坦钠冲管效果的重要因素。

    头孢哌酮钠舒巴坦钠；吸光度；排空次数；滴速

    [Abstract]Objective To study the influence of liquid surface level，times of emptying and dripping speed of tube washing of Murphy's dropper during intravenous injection on the effects of washing tube by 0.9%normal saline.Methods Absorbency of cefoperazone sodium and sulbactam sodium prepared with series of concentrations was measured by ultraviolet spectrophotometer，and standard curve was made.According to the differences of methylene blue，three influencing factors of liquid surface level，times of emptying and dripping speed of tube washing of Murphy's dropper were used to design the randomization protocol ......