叶红英 杨 帆 袁坚列 黄 坚

    浙江省金华市中心医院肾内科，浙江金华321000

    高血压脑出血发生急性肾损伤的危险因素研究

    叶红英杨帆袁坚列黄坚▲

    浙江省金华市中心医院肾内科，浙江金华321000

    目的探讨高血压脑出血发生急性肾损伤(AKI)的危险因素。方法回顾性分析2013年8月～2015年8月在我院神经外科收治的脑出血患者。采用Logistic回归分析高血压脑出血患者发生AKI的危险因素。结果共入选符合标准的高血压脑出血患者133例，其中AKI组占23.3%(31/133)，非AKI组占76.7%(102/133)。多因素回归分析显示，高血压病程≥10年(OR 2.385，95%CI 1.122～1.621，P<0.001)、贫血(OR 2.211，95%CI 1.754～2.551，P=0.022)和使用甘露醇(OR 1.513，95%CI 1.925～3.312，P<0.001)是AKI发生的独立危险因素。结论AKI是高血压脑出血常见的并发症，高血压病程长、贫血和使用甘露醇是高血压脑出血患者发生AKI的独立危险因素。

    高血压；脑出血；急性肾损伤；危险因素

    [Abstract]Objective To investigate the incidence and risk factors of acute kidney injury(AKI)after hypertensive cerebral hemorrhage.Methods Hypertensive cerebral hemorrhage patients who were admitted to Neurosurgical department from August 2013 to August 2015 were reviewed retrospectively.Logistic regression analysis was used to evaluate possible risk factors associated with hypertensive cerebral hemorrhage AKI.Results A total of selected 133 patients were enrolled in the study including 23.3%(31/133)patients in AKI group and 76.7%(102/133)patients without AKI group.Multivariate Logistic regression analysis showed that hypertension duration≥10 years(OR2.385 ......