房颤患者长间歇与心功能的相关性分析(1)
[摘要] 目的 探讨心房颤动患者长间歇与心功能的相关性。 方法 选取我院2012年3月～2017年6月房颤患者127例，分别记录患者的年龄、性别、超声心动图指标(LAD、LVEDD、LVSDD、IVS、LVPW、EF)及动态心电图中是否伴有长间歇及长间歇次数。根据患者是否伴有长间歇分为房颤伴长间歇组与房颤不伴长间歇组。 结果 房颤伴长间歇组与房颤不伴长间歇组比较，LAD显著增大(P<0.05)；两组间LVEDD、LVSDD、IVS、LVPW、EF比较，差异无统计学意义；相关分析示长间歇次数与LAD大小呈正相关(P<0.05)，与LVEDD、LVSDD、IVS、LVPW、EF之间无相关性。 结论 房颤伴长间歇会导致患者左房增大，可间接导致心功能的恶化，且随长间歇次数的增加而增加。
[关键词] 心房颤动；长间歇；心功能；左房大小
[中图分类号] R541 [文献标识码] A [文章编号] 1673-9701(2017)33-0013-03
[Abstract] Objective To investigate the correlation between long intervals and cardiac function in the patients with atrial fibrillation. Methods A total of 127 patients with atrial fibrillation who were enrolled in our hospital from March 2012 to June 2017 were selected. The age， sex， echocardiography indices(LAD， LVEDD， LVSDD， IVS， LVPW， EF)， whether the long intervals were accompanied in the dynamic electrocardiogram and the number of long intervals were recorded. According to whether the patients were accompanied with the long interval， the patients were divided into atrial fibrillation complicated with long interval group and atrial fibrillation without long interval group. Results LAD was significantly increased in the comparison between atrial fibrillation complicated with long interval group and atrial fibrillation without long interval group(P<0.05). LVEDD， LVSDD， IVS， LVPW and EF were not statistically different between the two groups. There was a positive correlation between the number of long intervals and LAD according to the correlation analysis(P<0.05)， which was not correlated with LVEDD， LVSDD， IVS， LVPW and EF. Conclusion Atrial fibrillation complicated with long interval can lead to the enlargement of left atrium， and indirectly lead to deterioration of cardiac function， which is increased along with the increase of the number of long intervals.
[Key words] Atrial fibrillation； Long interval； Cardiac function； Size of left atrium
心房顫动是常见的一种心律失常，危害全球人的健康，是当今社会的流行病，全球心房颤动的总患病率达0.08%～1.00%[1，2]；未来20年，房颤的发病率估计会翻倍[3]，至2030年仅欧洲每年预计新增房颤120 000～215 000例[4]。心力衰竭合并阵发性房颤的患者达33%，合并持续房颤的患者达44%，合并永久性房颤的患者高达56%[5]。房颤与心衰互为因果，房颤导致快速心律失常、房室不同步及节律的丧失都诱发和加重心功能的恶化及心脏结构的改变[6]。房颤时，起源于心房的局灶自律性增高，以及电激动在心房内发生折返形成紊乱的电活动，后者引起房室交界区产生生理性干扰和隐匿性传导，易致长RR间期的发生[7]。现就房颤伴长间歇对心功能的影响报道如下。
1 资料与方法
1.1一般资料
选择2012年3月～2017年6月在本院住院的心房颤动患者127例，其中男68例，女59例；年龄36～93岁，平均(69.63±11.86)岁；其中冠心病合并房颤78例，单纯房颤49例。患者均记录超声心动图指标(LAD、LVEDD、LVSDD、IVS、LVPW、EF)，并根据24 h动态心电图记录患者是否伴有长间歇及长间歇次数。长间歇次数0～823次120例，824～1646次3例，1647～2469次3例，2470～3292次0例，3293～4115次1例。将其分为A、B两组，A组为房颤伴长间歇组，B组为房颤不伴长间歇组。两组患者年龄、性别等方面比较，差异均无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(张凤 高志广 任国成 杜玉芝 许长存)
[关键词] 心房颤动；长间歇；心功能；左房大小
[中图分类号] R541 [文献标识码] A [文章编号] 1673-9701(2017)33-0013-03
[Abstract] Objective To investigate the correlation between long intervals and cardiac function in the patients with atrial fibrillation. Methods A total of 127 patients with atrial fibrillation who were enrolled in our hospital from March 2012 to June 2017 were selected. The age， sex， echocardiography indices(LAD， LVEDD， LVSDD， IVS， LVPW， EF)， whether the long intervals were accompanied in the dynamic electrocardiogram and the number of long intervals were recorded. According to whether the patients were accompanied with the long interval， the patients were divided into atrial fibrillation complicated with long interval group and atrial fibrillation without long interval group. Results LAD was significantly increased in the comparison between atrial fibrillation complicated with long interval group and atrial fibrillation without long interval group(P<0.05). LVEDD， LVSDD， IVS， LVPW and EF were not statistically different between the two groups. There was a positive correlation between the number of long intervals and LAD according to the correlation analysis(P<0.05)， which was not correlated with LVEDD， LVSDD， IVS， LVPW and EF. Conclusion Atrial fibrillation complicated with long interval can lead to the enlargement of left atrium， and indirectly lead to deterioration of cardiac function， which is increased along with the increase of the number of long intervals.
[Key words] Atrial fibrillation； Long interval； Cardiac function； Size of left atrium
心房顫动是常见的一种心律失常，危害全球人的健康，是当今社会的流行病，全球心房颤动的总患病率达0.08%～1.00%[1，2]；未来20年，房颤的发病率估计会翻倍[3]，至2030年仅欧洲每年预计新增房颤120 000～215 000例[4]。心力衰竭合并阵发性房颤的患者达33%，合并持续房颤的患者达44%，合并永久性房颤的患者高达56%[5]。房颤与心衰互为因果，房颤导致快速心律失常、房室不同步及节律的丧失都诱发和加重心功能的恶化及心脏结构的改变[6]。房颤时，起源于心房的局灶自律性增高，以及电激动在心房内发生折返形成紊乱的电活动，后者引起房室交界区产生生理性干扰和隐匿性传导，易致长RR间期的发生[7]。现就房颤伴长间歇对心功能的影响报道如下。
1 资料与方法
1.1一般资料
选择2012年3月～2017年6月在本院住院的心房颤动患者127例，其中男68例，女59例；年龄36～93岁，平均(69.63±11.86)岁；其中冠心病合并房颤78例，单纯房颤49例。患者均记录超声心动图指标(LAD、LVEDD、LVSDD、IVS、LVPW、EF)，并根据24 h动态心电图记录患者是否伴有长间歇及长间歇次数。长间歇次数0～823次120例，824～1646次3例，1647～2469次3例，2470～3292次0例，3293～4115次1例。将其分为A、B两组，A组为房颤伴长间歇组，B组为房颤不伴长间歇组。两组患者年龄、性别等方面比较，差异均无统计学意义(P>0.05)，具有可比性。, http://www.100md.com(张凤 高志广 任国成 杜玉芝 许长存)