[摘要] 目的 研究住院痴呆患者伴发谵妄的相关疾病特征，分析痴呆叠加谵妄的危险因素。 方法 研究对象为符合DSM-IV诊断标准的痴呆患者共165例，基线期分别以CDR、MMSE、NPI及ADL评估疾病严重度、认知功能、精神行为症状及功能，按住院8周内是否伴发谵妄，将患者分为无谵妄组和有谵妄组，比较两组疾病特征的差异，进行Logistic回归分析。 结果 老年痴呆患者合并谵妄的比例为29.09%；痴呆患者发生谵妄的危险因素包括高龄、丧偶、血管性痴呆、总体疾病严重度及精神行为症状高评分。 结论 痴呆患者伴发谵妄的发生率较高，可针对相关危险因素进行预防和早期干预。

    [关键词] 痴呆；谵妄；住院患者；危险因素

    [中图分类号] R749.1+6 [文献标识码] B [文章编号] 1673-9701(2017)35-0072-03

    [Abstract] Objective To investigate the characteristics of related diseases associated with delirium in hospitalized patients with dementia and to analyze the risk factors of dementia complicated with delirium. Methods A total of 165 patients with dementia who were in compliance with the DSM-IV diagnostic criteria were selected as the research subjects. At the baseline stage ......