综上所述，右美托咪定能改善冠心病腹腔镜胆囊切除术患者的高凝状态，并明显抑制气管拔管期引起的应激反应，不延迟术后苏醒，不增加手术出血量，适用于冠心病患者围术期。

    [参考文献]

    [1]Erer D，Ozer A，Arslan M，et al.The protective effects of dexmedetomidine on liver injury-induced myocardial ischemia reperfusion[J]. Bratisl Lek Listy，2014，115(7)：422-426.

    [2]Sulaiman S，Karthekeyan RB，Vakamudi M，et al.The effects of dexmedetomidine on attenuation of stress response to endotracheal intubation in patients undergoing elective off-pump coronary artery bypass grafting[J]. Ann Card Anaesth ......