[摘要] 目的 分析重症医学科肺部感染患者肺泡灌洗液病原菌分布及其耐药情况，以指导临床抗菌药物使用。方法 回顾性分析2016年6月～2017年5月重症医学科肺部感染患者肺泡灌洗液分离的细菌培养结果及耐药性分析。采用WHONET5.4软件进行药敏结果统计。 结果 共分离出非重复菌株137株，革兰阴性菌共122株，占比89.1%，以鲍曼不动杆、铜绿假单胞菌、肺炎克雷伯菌为主，分别占24.1%、21.9%、14.6%。革兰阳性菌菌株共15株，占比10.9%，以金黄色葡萄球菌为主，占比7.3%，对万古霉素及替考拉宁敏感率为100.0%。 结论 重症医学科肺部感染患者肺泡灌洗液的主要病原菌为革兰阴性菌，细菌多重耐药现象明显，开展监测及合理用药是控制感染和耐药菌出现的关键。

    [关键词] 重症医学科；肺泡灌洗液；病原菌；耐药性

    [中图分类号] R563.1 [文献标识码] B [文章编号] 1673-9701(2018)07-0089-04

    [Abstract] Objective To analyze the distribution and drug resistance of alveolar lavage fluid in patients with pulmonary infection in the Department of Critical Care Medicine to guide the clinical use of antibacterial drugs. Methods The bacterial culture results and antibiotic resistance of pulmonary alveolar lavage fluid isolated from patients with pulmonary infection in the Department of Critical Care Medicine from June 2016 to May 2017 were retrospectively analyzed. WHONET5.4 software was used for drug susceptibility results statistics. Results A total of 137 non-repetitive strains were isolated ......