[摘要] 目的 探讨急性白血病患者住院期间合并肛周感染的临床特点及高危因素，为临床防治提供依据。 方法 对某三甲医院血液科2012年1月～2016年12月收治的319例急性白血病患者的临床资料进行回顾性分析。采用SPSS17.0软件行单因素分析和多因素Logistic回归分析肛周感染的危险因素。 结果 319例急性白血病患者合并肛周感染38例，肛周感染率11.9%，其中肛周脓肿15例，炎性外痔10例，肛周单纯皮肤感染7例，肛瘘6例；年龄≥60岁、粒细胞缺乏、既往有肛裂或痔史是急性白血病患者合并肛周感染的独立危险因素。 结论 急性白血病患者肛周感染以肛周脓肿多见，内科治疗为主；应针对肛周感染危险因素采取积极措施，以改善患者生活质量及提高疗效。

    [关键词] 白血病；肛周感染；危险因素；多因素Logistic回归分析；生活质量

    [中图分类号] R733.71 [文献标识码] B [文章编号] 1673-9701(2018)21-0110-03

    [Abstract] Objective To investigate the clinical characteristics and risk factors of acute leukemia patients with perianal infection during hospitalization and to provide the basis for clinical prevention and treatment. Methods The clinical data of 319 patients with acute leukemia admitted in Department of Hematology in a top three hospital from January 2012 to December 2016 were retrospectively analyzed. SPSS 17.0 software was used to analyze risk factors of perianal infection by univariate analysis and multivariate Logistic regression analysis. Results There were 38 cases of perianal infection in 319 cases of acute leukemia ......