氟哌噻吨美利曲辛片联合多塞平治疗功能性腹痛的临床研究(1)
[摘要] 目的 探讨氟哌噻吨美利曲辛片联合多塞平对功能性腹痛的治疗效果。 方法 选取80例根据汉密顿抑郁量表(HAMD)及汉密顿焦虑量表(HAMA)评分后诊断为轻中度焦虑或抑郁的功能性腹痛患者为研究对象,随机分为治疗组40例,对照组40例。对照组患者给予雷贝拉唑、莫沙必利、匹维溴铵治疗,治疗组患者给予雷贝拉唑、莫沙必利、匹维溴铵并加用氟哌噻吨美利曲辛联合多塞平治疗。观察比较治疗第4及第8周末两组患者焦虑抑郁评分、功能性腹痛症状缓解率及腹痛症状评分。 结果 治疗第4周及8周末治疗组患者焦虑抑郁评分较对照组有明显下降,功能性腹痛各症状缓解率明显高于对照组,腹痛症状评分低于对照组,差异具有统计学意义(P<0.05)。 结论 氟哌噻吨美利曲辛联合多塞平可改善功能性腹痛患者焦虑抑郁状态,从而改善临床症状,提高其生活质量。[关键词] 功能性腹痛;氟哌噻吨美利曲辛;多塞平;焦虑抑郁
[中图分类号] R572 [文献标识码] B [文章编号] 1673-9701(2018)25-0035-03
[Abstract] Objective To investigate the efficacy of flupenthixol melitracen tablets combined with doxepin in the treatment of functional abdominal pain. Methods 80 functional abdominal pain patients diagnosed with mild to moderate anxiety or depression after the HAMD and HAMA scores were selected and randomly divided into treatment group(n=40) and control group(n=40). Patients in the control group were treated with rabeprazole ......
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