MRI在鉴别诊断老年骨质疏松性骨折与转移瘤骨折中的应用价值(1)
[摘要] 目的 分析MRI在鉴别诊断老年骨质疏松性骨折与转移瘤骨折中的应用。 方法 回顾性分析我院自2012年1月~2016年12月收治的40例老年骨质疏松性骨折患者及40例转移瘤骨折患者的临床资料,观察两类患者的MRI影像学表现,对比二者之间的差异。 结果 骨质疏松性骨折患者与转移瘤患者的MRI诊断结果中T2WI低信号及椎体形态改变中的扁平形检出率相比无明显差异(P>0.05)。骨质疏松性骨折患者与转移瘤患者的MRI诊断结果中T1WI低信号、高信号,T2WI高信号及椎体形态改变中的楔形、凹陷形、后缘成角及后缘膨隆检出率相比,差异具有统计学意义(P<0.05)。 结论 利用MRI鉴别诊断老年骨质疏松性骨折与转移瘤骨折具有重要的应用价值。
[关键词] MRI;鉴别诊断;老年骨质疏松性骨折;转移瘤;压缩性骨折
[中图分类号] R445.2;R683 [文献标识码] B [文章编号] 1673-9701(2018)27-0120-04
[Abstract] Objective To investigate and analyze the application value of MRI on the differential diagnosis between aged osteoporotic fracture and pathologic fracture of metastatic tumor. Methods Clinical records of 40 patients with aged osteoporotic fracture and 40 patients with pathologic fracture of metastatic tumor in our hospital from January 2012 to December 2016 were retrospectively analyzed. The radiologic performance of MRI in two kinds of patients was observed and the difference between them was compared. Results There were no significant differences of T2WI low signal and detection rate of flat shape in the morphological changes of vertebral body between the MRI diagnostic results of patients with osteoporotic fracture and patients with metastatic tumor(P>0.05). There were significant differences of T1WI low and high signal, T2WI high signal as well as the detection rates of wedge shape, depression shape, subsequent angle formation and posterior margin swelling in the morphological changes of vertebral body between the MRI diagnostic results of patients with osteoporotic fracture and patients with metastatic tumor(P<0.05). Conclusion The application of MRI in the differential diagnosis between aged osteoporotic fracture and pathologic fracture of metastatic tumor is significantly valuable.
[Key words] MRI; Differential diagnosis; Aged osteoporotic fracture; Metastatic tumor; Compression fracture
椎體压缩性骨折作为临床上一类发病率较高的骨科疾病,大量资料显示,由于骨质疏松所引起的良性骨折以及转移瘤导致的恶性压缩性骨折多发生在老年患者中,无论是何种骨折均会对患者的肢体功能及生活质量造成较大的影响[1]。由于部分原发性肿瘤的生长部位较为隐匿,且随着近年来转移瘤的发病率呈逐年上升的趋势,但对转移瘤进行早期诊断与治疗能够减少对脊柱造成的损伤,获得更好的预后[2]。因此,对压缩性骨折进行早期诊断与鉴别至关重要,现我院针对MRI在鉴别诊断老年骨质疏松性骨折与转移瘤骨折中应用展开分析,现报道如下。
1 资料与方法
1.1 一般资料
回顾性分析我院自2012年1月~2016年12月收治的40例老年骨质疏松性骨折患者及40例转移瘤骨折患者的临床资料。老年骨质疏松性骨折患者经过骨密度测量系统证实,其中男25例,女15例,年龄61~74岁,平均(69.12±3.34)岁。转移瘤骨折患者经过病理结果证实,疾病类型包括乳腺癌13例,肺癌11例,前列腺癌8例,肝癌5例,直肠癌3例,其中男24例,女16例,年龄62~75岁,平均(68.12±4.11)岁。两组患者一般资料均无显著性差异(P>0.05),具有可比性。全部患者均签署关于本次试验的知情权同意书,试验符合医学伦理会批准审核。
1.2方法
观察两类患者的MRI影像学表现,对比二者之间的差异。检查方法:采用西门子公司生产的1.5 T MAGNETOM Avanto测量,指导患者摆放仰卧位,于静息状态下指导患者进行安静的呼吸。给予常规SE序列:矢状位是T1WI、T2WI,横轴位:T2WI,矢状位、轴位:T1WI进行增强扫描,脂肪预饱T2WI(T2WIFS、TW 80~120 ms、TR 3000~4000 ms);横轴位的T2WI(TE 80~120 ms、TR 3000~4000 ms),矩阵为256×512~332×640,层厚为4 mm,层距为1 mm[3]。, http://www.100md.com(张侠 张雷 郑军 高源统 王晓阳)
[关键词] MRI;鉴别诊断;老年骨质疏松性骨折;转移瘤;压缩性骨折
[中图分类号] R445.2;R683 [文献标识码] B [文章编号] 1673-9701(2018)27-0120-04
[Abstract] Objective To investigate and analyze the application value of MRI on the differential diagnosis between aged osteoporotic fracture and pathologic fracture of metastatic tumor. Methods Clinical records of 40 patients with aged osteoporotic fracture and 40 patients with pathologic fracture of metastatic tumor in our hospital from January 2012 to December 2016 were retrospectively analyzed. The radiologic performance of MRI in two kinds of patients was observed and the difference between them was compared. Results There were no significant differences of T2WI low signal and detection rate of flat shape in the morphological changes of vertebral body between the MRI diagnostic results of patients with osteoporotic fracture and patients with metastatic tumor(P>0.05). There were significant differences of T1WI low and high signal, T2WI high signal as well as the detection rates of wedge shape, depression shape, subsequent angle formation and posterior margin swelling in the morphological changes of vertebral body between the MRI diagnostic results of patients with osteoporotic fracture and patients with metastatic tumor(P<0.05). Conclusion The application of MRI in the differential diagnosis between aged osteoporotic fracture and pathologic fracture of metastatic tumor is significantly valuable.
[Key words] MRI; Differential diagnosis; Aged osteoporotic fracture; Metastatic tumor; Compression fracture
椎體压缩性骨折作为临床上一类发病率较高的骨科疾病,大量资料显示,由于骨质疏松所引起的良性骨折以及转移瘤导致的恶性压缩性骨折多发生在老年患者中,无论是何种骨折均会对患者的肢体功能及生活质量造成较大的影响[1]。由于部分原发性肿瘤的生长部位较为隐匿,且随着近年来转移瘤的发病率呈逐年上升的趋势,但对转移瘤进行早期诊断与治疗能够减少对脊柱造成的损伤,获得更好的预后[2]。因此,对压缩性骨折进行早期诊断与鉴别至关重要,现我院针对MRI在鉴别诊断老年骨质疏松性骨折与转移瘤骨折中应用展开分析,现报道如下。
1 资料与方法
1.1 一般资料
回顾性分析我院自2012年1月~2016年12月收治的40例老年骨质疏松性骨折患者及40例转移瘤骨折患者的临床资料。老年骨质疏松性骨折患者经过骨密度测量系统证实,其中男25例,女15例,年龄61~74岁,平均(69.12±3.34)岁。转移瘤骨折患者经过病理结果证实,疾病类型包括乳腺癌13例,肺癌11例,前列腺癌8例,肝癌5例,直肠癌3例,其中男24例,女16例,年龄62~75岁,平均(68.12±4.11)岁。两组患者一般资料均无显著性差异(P>0.05),具有可比性。全部患者均签署关于本次试验的知情权同意书,试验符合医学伦理会批准审核。
1.2方法
观察两类患者的MRI影像学表现,对比二者之间的差异。检查方法:采用西门子公司生产的1.5 T MAGNETOM Avanto测量,指导患者摆放仰卧位,于静息状态下指导患者进行安静的呼吸。给予常规SE序列:矢状位是T1WI、T2WI,横轴位:T2WI,矢状位、轴位:T1WI进行增强扫描,脂肪预饱T2WI(T2WIFS、TW 80~120 ms、TR 3000~4000 ms);横轴位的T2WI(TE 80~120 ms、TR 3000~4000 ms),矩阵为256×512~332×640,层厚为4 mm,层距为1 mm[3]。, http://www.100md.com(张侠 张雷 郑军 高源统 王晓阳)