[摘要] 目的 探析慢性乙型肝炎患者外周血调节性T淋巴细胞(Treg)检测的临床意义。 方法 选取2016年1月～2018年6月我院收治的60例慢性乙型肝炎患者为观察组，选取同期体检的60例健康者为对照组，均给予外周血检测，比较两组检验结果。 结果 观察组Treg、TrI、Th17百分比均高于对照组，差异显著(P<0.05)。观察组IL-10、IL-17水平高于对照组，差异显著(P<0.05)。观察组CD3+、CD4+百分比低于对照组，CD8+百分比、CD4+ C25+ Treg百分比高于对照组，差异显著(P<0.05)。 结论 慢性乙型肝炎患者外周血Treg水平明显升高，且Th17参与致病过程，因此，通过临床检测及调控，有助于提高患者诊治效果，临床应用与借鉴价值极高。

    [关键词] 慢性乙型肝炎;外周血;调节性T淋巴细胞;病因

    [中图分类号] R446 [文献标识码] B [文章编号] 1673-9701(2018)35-0139-03

    [Abstract] Objective To explore the clinical significance of detection of peripheral blood regulatory T lymphocytes(Treg)in patients with chronic hepatitis B. Methods Sixty patients with chronic hepatitis B admitted to our hospital from January 2016 to June 2018 were enrolled in the observation group. Another 60 healthy subjects who underwent physical examination during the same time period were selected as the control group. All subjects were tested for peripheral blood and the results of the two groups were compared. Results The percentages of Treg ......