平秘脏腑推拿改善肿瘤患者进食欲望的临床研究(1)
[摘要] 目的 观察平秘脏腑推拿改善肿瘤患者进食欲望的临床疗效。 方法 将2015年7月～2018年6月我院100例符合肿瘤相关厌食症状的患者随机分为两组，对照组予营养支持及肿瘤科专科治疗;治疗组在此基础上加用平秘脏腑推拿手法。疗程开始前及结束后，分别使用体重、生化指标、食欲VAS评分及Anderson症状评分对疗效进行评估。 结果 疗程结束后评估，治疗组患者体重为(53.53±1.20)kg，与对照组比较无明显优势(P>0.05);治疗组总蛋白及白蛋白水平分别为(68.26±1.26)g/L及(38.15±0.54)g/L，亦未优于对照组指标(P>0.05)。但治疗组VAS食欲评分为(4.08±0.21)分，对照组为(5.13±0.19)分;治疗组Anderson症状评分为(33.57±0.46)分，对照组为(38.48±0.43)分，组间比较差异均具有统计学意义(P<0.05)。 结论 平秘脏腑推拿可提高肿瘤相关厌食患者的进食欲望，缓解疲劳乏力等不适症状。
[关键词] 平秘脏腑推拿;肿瘤相关厌食;进食欲望
[中图分类号] R273 [文献标识码] B [文章编号] 1673-9701(2019)14-0128-06
[Abstract] Objective To observe the clinical efficacy of Pingmi Zangfu massage in improving the eating desire of patients with tumor-related anorexia. Methods 100 patients with tumor-associated anorexia symptoms from July 2015 to June 2018 were randomly divided into two groups. The control group received nutritional support and oncology specialist treatment. The treatment group was added with Pingmi Zangfu massage on the above basis. Before and after the start of the treatment， the effects were evaluated using body weight， biochemical indicators， appetite VAS scores， and Anderson symptom scores. Results After treatment， the body weight of the patients in the treatment group was(53.53±1.20)kg， which had no significant advantage compared with the control group(P>0.05). And the total protein and albumin levels in the treatment group were(68.26±1.26) g/L and(38.15±0.54) g/L， respectively， which was not superior to the control group(P>0.05). However， the VAS appetite score was(4.08±0.21)points in the treatment group and(5.13±0.19)points in the control group. The Anderson symptom score was(33.57±0.46)points in the treatment group and(38.48±0.43)points in the control group. The differences were statistically significant(P<0.05). Conclusion Pingmi Zangfu massage can improve the eating desire of patients with tumor-related anorexia and relieve symptoms such as fatigue and fatigue.
[Key words] Pingmi Zangfu massage; Tumor-related anorexia; Eating desire
腫瘤相关厌食症状是引起癌症患者中后期营养不良和免疫功能下降的重要因素之一，不仅严重降低了肿瘤患者的生活质量、延长住院时间;还直接导致患者对放化疗耐受能力的下降，无法接受或完成完整的抗肿瘤方案，成为部分肿瘤患者死亡的直接诱因[1-2]。引起肿瘤相关厌食症状的病因较多，发病机制复杂，故缺少高质量临床证据支持的特效疗法。目前采用的孕激素、沙利度胺等药物治疗方案，副作用较为严重，可应用范围受到限制[3]。所以课题组开展平秘脏腑推拿对肿瘤相关厌食患者进食欲望及生存质量改善的临床试验，期望深入探索该病中医发病机制，运用合理的治则治法，寻找抗厌食症状的补充替代方案，对提高肿瘤患者生活质量，改善愈后等方面具有积极的实践意义，现报道如下。
1 资料与方法
1.1 一般资料
研究纳入对象均为2015年7月～2018年6月本院肿瘤科招募的具有厌食症状的肿瘤患者100例。将患者使用计算机软件生成随机数字表，随机分为治疗组50例，年龄49～79岁，肿瘤病理确诊后病程7～96个月;对照组50例，年龄51～77岁，病程9～78个月。两组纳入对象组间基线资料比较，差异无统计学意义(P>0.05)，具有可比性，见表1。, 百拇医药(王睿 詹强 孙戴)
[关键词] 平秘脏腑推拿;肿瘤相关厌食;进食欲望
[中图分类号] R273 [文献标识码] B [文章编号] 1673-9701(2019)14-0128-06
[Abstract] Objective To observe the clinical efficacy of Pingmi Zangfu massage in improving the eating desire of patients with tumor-related anorexia. Methods 100 patients with tumor-associated anorexia symptoms from July 2015 to June 2018 were randomly divided into two groups. The control group received nutritional support and oncology specialist treatment. The treatment group was added with Pingmi Zangfu massage on the above basis. Before and after the start of the treatment， the effects were evaluated using body weight， biochemical indicators， appetite VAS scores， and Anderson symptom scores. Results After treatment， the body weight of the patients in the treatment group was(53.53±1.20)kg， which had no significant advantage compared with the control group(P>0.05). And the total protein and albumin levels in the treatment group were(68.26±1.26) g/L and(38.15±0.54) g/L， respectively， which was not superior to the control group(P>0.05). However， the VAS appetite score was(4.08±0.21)points in the treatment group and(5.13±0.19)points in the control group. The Anderson symptom score was(33.57±0.46)points in the treatment group and(38.48±0.43)points in the control group. The differences were statistically significant(P<0.05). Conclusion Pingmi Zangfu massage can improve the eating desire of patients with tumor-related anorexia and relieve symptoms such as fatigue and fatigue.
[Key words] Pingmi Zangfu massage; Tumor-related anorexia; Eating desire
腫瘤相关厌食症状是引起癌症患者中后期营养不良和免疫功能下降的重要因素之一，不仅严重降低了肿瘤患者的生活质量、延长住院时间;还直接导致患者对放化疗耐受能力的下降，无法接受或完成完整的抗肿瘤方案，成为部分肿瘤患者死亡的直接诱因[1-2]。引起肿瘤相关厌食症状的病因较多，发病机制复杂，故缺少高质量临床证据支持的特效疗法。目前采用的孕激素、沙利度胺等药物治疗方案，副作用较为严重，可应用范围受到限制[3]。所以课题组开展平秘脏腑推拿对肿瘤相关厌食患者进食欲望及生存质量改善的临床试验，期望深入探索该病中医发病机制，运用合理的治则治法，寻找抗厌食症状的补充替代方案，对提高肿瘤患者生活质量，改善愈后等方面具有积极的实践意义，现报道如下。
1 资料与方法
1.1 一般资料
研究纳入对象均为2015年7月～2018年6月本院肿瘤科招募的具有厌食症状的肿瘤患者100例。将患者使用计算机软件生成随机数字表，随机分为治疗组50例，年龄49～79岁，肿瘤病理确诊后病程7～96个月;对照组50例，年龄51～77岁，病程9～78个月。两组纳入对象组间基线资料比较，差异无统计学意义(P>0.05)，具有可比性，见表1。, 百拇医药(王睿 詹强 孙戴)