益气活血通络法对气虚血瘀型慢性阻塞性肺疾病急性发作(AECOPD)血小板活化指标的影响(1)
[摘要] 目的 評价对气虚血瘀型慢性阻塞性肺疾病急性发作(AECOPD)患者应用益气活血通络法的临床价值以及对其血小板活化指标的影响。 方法 选取2017年9月～2019年5月我院收治的136例慢性阻塞性肺疾病急性发作患者为研究对象，采用数字随机表法将其分成2组(试验组与对照组)，每组68例。其中对照组运用临床常规治疗措施，试验组在此基础上运用益气活血通络法治疗。对其治疗前后血小板活化指标、中医症候积分等数据进行统计分析。 结果 ①试验组与对照组治疗前中医证候积分比较，差异无统计学意义(P>0.05)，治疗后试验组评分低于对照组同等数据评分，差异有统计学意义(P<0.05);②两组患者治疗前D-二聚体、PAC-1、CD62p比较，差异无统计学意义(P>0.05)，治疗后试验组D-二聚体、PAC-1、CD62p等均低于对照组，差异有统计学意义(P<0.05);③试验组治疗总有效率97.06%(66/68)高于对照组治疗总有效率88.24%(60/68)，差异有统计学意义(P<0.05)。 结论 针对慢性阻塞性肺疾病急性发作患者给予常规治疗基础之上开展益气活血通络法治疗，相比常规治疗效果显著，对改善其血小板活化指标具有重要帮助，是临床治疗该种疾病的有效措施。
[关键词] 气虚血瘀型;慢性阻塞性肺疾病;益气活血通络法;血小板活化
[中图分类号] R259 [文献标识码] B [文章编号] 1673-9701(2019)35-0118-04
Effect of Yiqi Huoxue Tongluo method on platelet activation index of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with qi deficiency and blood stasis type
HU Xiuliu1 HE Fei2 WANG Yanpeng1
1.Department of Emergency Internal Medicine， Hangzhou Red Cross Hospital， Hangzhou 310003， China; 2.Department of Respiratory Medicine， Hangzhou Red Cross Hospital， Hangzhou 310003， China
[Abstract] Objective To evaluate the clinical value of Yiqi Huoxue Tongluo method in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with qi deficiency and blood stasis type and its effect on platelet activation index. Methods 136 patients with acute exacerbation of chronic obstructive pulmonary disease admitted to our hospital from September 2017 to May 2019 were selected for study. The patients were divided into two groups by numerical random table method including experimental group and control group， with 68 cases in each group. The control group used clinical routine treatment measures， and the experimental group was treated with Yiqi Huoxue Tongluo method on this basis. Statistical analysis was performed on the data such as platelet activation index and TCM symptom scores before and after treatment. Results 1.There were no significant differences in TCM symptom scores between the experimental group and the control group before treatment. The scores of the experimental group were lower than those of the control group， with statistically significant difference(P<0.05). 2.There was no significant difference in D-dimer， PAC-1， CD62p before treatment between the two groups(P>0.05). The D-dimer， PAC-1 and CD62p in the experimental group were lower than those in the control group. There was statistical significance between the two groups. There was a significant difference between the treatment group and the control group (P<0.05). The total effective rate of the treatment group was 97.06% (66/68)， which was higher than the total effective rate of the control group [88.24% (60/68)]. There was significant difference between two groups (P<0.05). Conclusion For the patients with acute exacerbation of chronic obstructive pulmonary disease， the treatment of Yiqi Huoxue Tongluo on the basis of routine treatment is more effective than conventional treatment， which is of great help to improve the platelet activation index. It is the effective clinical treatment measures of this disease., http://www.100md.com(胡修六 何飞 王艳鹏)
[关键词] 气虚血瘀型;慢性阻塞性肺疾病;益气活血通络法;血小板活化
[中图分类号] R259 [文献标识码] B [文章编号] 1673-9701(2019)35-0118-04
Effect of Yiqi Huoxue Tongluo method on platelet activation index of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with qi deficiency and blood stasis type
HU Xiuliu1 HE Fei2 WANG Yanpeng1
1.Department of Emergency Internal Medicine， Hangzhou Red Cross Hospital， Hangzhou 310003， China; 2.Department of Respiratory Medicine， Hangzhou Red Cross Hospital， Hangzhou 310003， China
[Abstract] Objective To evaluate the clinical value of Yiqi Huoxue Tongluo method in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with qi deficiency and blood stasis type and its effect on platelet activation index. Methods 136 patients with acute exacerbation of chronic obstructive pulmonary disease admitted to our hospital from September 2017 to May 2019 were selected for study. The patients were divided into two groups by numerical random table method including experimental group and control group， with 68 cases in each group. The control group used clinical routine treatment measures， and the experimental group was treated with Yiqi Huoxue Tongluo method on this basis. Statistical analysis was performed on the data such as platelet activation index and TCM symptom scores before and after treatment. Results 1.There were no significant differences in TCM symptom scores between the experimental group and the control group before treatment. The scores of the experimental group were lower than those of the control group， with statistically significant difference(P<0.05). 2.There was no significant difference in D-dimer， PAC-1， CD62p before treatment between the two groups(P>0.05). The D-dimer， PAC-1 and CD62p in the experimental group were lower than those in the control group. There was statistical significance between the two groups. There was a significant difference between the treatment group and the control group (P<0.05). The total effective rate of the treatment group was 97.06% (66/68)， which was higher than the total effective rate of the control group [88.24% (60/68)]. There was significant difference between two groups (P<0.05). Conclusion For the patients with acute exacerbation of chronic obstructive pulmonary disease， the treatment of Yiqi Huoxue Tongluo on the basis of routine treatment is more effective than conventional treatment， which is of great help to improve the platelet activation index. It is the effective clinical treatment measures of this disease., http://www.100md.com(胡修六 何飞 王艳鹏)