[摘要] 慢性粒细胞白血病患者在使用酪氨酸激酶抑制剂(TKIs)治疗后彻底改变了预后。许多育龄期患者有强烈的生育需求，由于TKIs存在妊娠毒性及停药或致疾病进展，目前该方面仍面临许多挑战。本文报道了11例使用伊马替尼(IM)治疗CML的女性患者的妊娠结局及疾病预后，以提高对该类患者妊娠的临床认识，为有生育需求的CML女性患者制定最佳治疗方案。

    [关键词] 慢性粒细胞白血病;伊马替尼;妊娠;母乳

    [中图分类号] R733.72 [文献标识码] C [文章编号] 1673-9701(2020)26-0152-05

    [Abstract] Patients with chronic myelogenous leukemia have completely changed their prognosis after treatment with tyrosine kinase inhibitors(TKIs). Many patients of childbearing age have strong fertility needs. Due to TKIs pregnancy toxicity and withdrawal may lead to disease progression ......