周磊 吴晓兰 徐凤娥

    [摘要] 目的 通過对不同度数青少年近视验配角膜塑形镜(OK镜)两年后的近视控制效果的比较，探讨配戴OK镜后近视控制效果与近视度数的关系。 方法 采用前瞻性非随机对照研究。收集2018年1～3月在我院视光专科验配角膜塑形镜的青少年近视患者100例，根据等效球镜度不同分为近视低度数组(-1.25～-2.50 D)和中度数组(-3.75～-5.00 D)。随访2年，观察和记录两组的性别、年龄、度数、角膜曲率和眼轴以及戴镜后6、12、18、24个月的眼轴数据。对基线数据及眼轴的变化情况进行统计学分析，并监测不良反应。 结果 共94例(177眼)完成两年随访。其中低度数组108眼，中度数组69眼。两组等效球镜度(D)分别为(-2.04±0.44)D和(-4.20±0.63)D，差异有统计学意义(t=26.936，P<0.001);眼轴分别为(24.33±0.71)mm和(25.20±0.67)mm，差异有统计学意义(t=8.144，P<0.001)，年龄、性别和角膜曲率比较，差异无统计学意义。中度数组配戴OK镜两年后眼轴增加量为(0.27±0.11)mm，小于低度数组的(0.57±0.36)mm，差异有统计学意义(t=7.384，P<0.001)，组内各时间点眼轴变化比较，差异有统计学意义(P<0.001)。 结论 中度数组配戴OK镜两年后眼轴增长速度明显低于低度数组，近视控制的效果中度数组优于低度数组。相对高度数的青少年近视配戴OK镜后近视控制的效果好，更多的周边近视性离焦能更好地抑制眼轴的增长。

    [关键词] 角膜塑形镜;近视;眼轴;周边离焦

    [中图分类号] R778.11? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2020)32-0081-04

    [Abstract] Objective To compare the myopia control effect of young people with different degrees of myopia after two years of fitting with orthokeratology lenses(OK lenses) to explore the relationship between myopia control effect and myopia degree after wearing OK lenses. Methods Prospective non-randomized controlled study was conducted. One hundred juvenile myopia patients who were fitted with orthokeratology lenses in the Optometry Specialty of Ningbo Eye Hospital from January to March 2018 were collected and grouped according to the equivalent spherical degree. They were divided into the low myopia group(-1.25 D to -2.50 D) and the medium myopia group(-3.75 D to -5.00 D). They were followed up for two years. The gender ......