董灵丽

    [摘要] 目的 探討克罗米芬联合二甲双胍治疗多囊卵巢综合征合并不孕患者的临床效果。 方法 回顾性选取2018年1月至2020年1月我院多囊卵巢综合征合并不孕患者100例，依据治疗方法分为二甲双胍联合克罗米芬治疗组(联合治疗组，n=50)和克罗米芬单独治疗组(单独治疗组，n=50)，统计分析两组患者BMI、FPG、FINS、内膜厚度、性激素水平、促排卵时间、成熟卵泡个数、排卵、妊娠、早孕流产情况。 结果 联合治疗组治疗后较治疗前BMI、FPG、FINS降低幅度、内膜厚度增厚幅度均显著高于单独治疗组(P0.05)。联合治疗组患者妊娠率为50.00%(25/50)，显著高于单独治疗组的20.00%(10/50)(P0.05)。 结论 克罗米芬联合二甲双胍治疗多囊卵巢综合征合并不孕患者的临床效果较克罗米芬单独治疗好。

    [关键词] 多囊卵巢综合征合并不孕;克罗米芬;二甲双胍;内膜厚度;性激素水平;排卵;妊娠

    [中图分类号] R711.6? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)06-0079-04

    The clinical effect of metformin combined with clomiphene on the patients with polycystic ovary syndrome complicated with infertility

    DONG Lingli

    Family Planning Service Centre， Heze Women and Children′s Hospital in Shandong Province， Heze? ?274000， China

    [Abstract] Objective To investigate the clinical effect of clomiphene combined with metformin in the patients with polycystic ovary syndrome complicated with infertility. Methods A total of 100 patients with polycystic ovary syndrome complicated with infertility in our hospital from January 2018 to January 2020 were retrospectively analyzed. According to the treatment methods ......