戴彧君 陈志祥 张弛 佘艳军

    [摘要] 抗中性粒细胞胞浆抗体(ANCA)相关性血管炎(AAV)是一种累及多个系统且呈坏死性的血管炎。该病所涉及的系统比较零散，典型症状不明显，因此十分容易引起误诊、漏诊。且如果不进行及时有效的治疗，该病十分容易发展为终末期肾病，对患者的生命健康造成严重影响。因此，对该病进行早期诊断并进行及时合理治疗，控制病情的发展，可使患者预后得到明显改善。临床上常采用糖皮质激素联合细胞毒性药物作为AAV首选治疗方法。对于需要透析或血肌酐迅速升高、合并弥漫性肺出血、AAV和抗GBM肾炎重叠综合征的患者，建议加用血浆置换。由于AAV临床表现复杂，且缺少特异性实验室检查。因此临床医护人员需提高对该疾病的认识，才能及时准确地诊断并制定治疗方案。本文就1例AAV累及肾脏且需要透析者进行详细报道。

    [关键词] ANCA;相关性血管炎;终末期肾病;透析

    [中图分类号] R593.2? ? ? ? ? [文献标识码] C? ? ? ? ? [文章编号] 1673-9701(2021)06-0145-03

    Clinical analysis of a dialysis patient with anti-neutrophil cytoplasmic antibody-associated vasculitis

    Dai Yujun? ?CHEN Zhixiang? ?ZHANG Chi? ?SHE Yanjun

    Departments of Nephrology， Southern Central Hospital of Yunnan Province， Mengzi? ?661100， China.

    [Abstract] Anti-neutrophil cytoplasmic antibody(ANCA)-associated vasculitis (AAV) is a kind of necrotizing vasculitis involving multiple systems. The system involved in the disease is scattered and the typical symptoms are not obvious， so the misdiagnosis and missed diagnosis are frequently occurred. Moreover ......