侯琳琳

    [摘要] 目的 探討替罗非班用于急性进展性脑梗死患者治疗中的临床疗效及治疗安全性。 方法 选取2019年1—12月在我院接受治疗的急性进展性脑梗死患者88例，依据随机数字表法分为两组，每组各44例。对照组实施常规氯吡格雷+拜阿司匹林治疗的，观察组实施常规用药+替罗非班治疗。比较两组护理干预后患者日常生活能力、神经功能改善情况、对血小板功能影响情况以及治疗期间不良事件发生情况。 结果 观察组治疗7 d、14 d后的NIHSS评分显著低于对照组，差异有统计学意义(P0.05)。 结论 将替罗非班应用于急性进展性脑梗死患者治疗中可有效改善患者日常生活能力以及神经功能，对血小板活化有较强的抑制效果，且治疗安全性较高，有较高的临床应用价值。

    [关键词] 急性进展性脑梗死;替罗非班;血小板活化;临床效果

    [中图分类号] R743.3? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)13-0046-04

    Observation on the clinical efficacy and safety of tirofiban in patients with acute progressive cerebral infarction

    HOU Linlin

    The Third Department of Neurology， the First People′s Hospital of Shenyang City， Shenyang? ?110041， China

    [Abstract] Objective To explore the clinical efficacy and safety of tirofiban in the treatment of patients with acute progressive cerebral infarction. Methods A total of 88 patients with acute progressive cerebral infarction who were treated in our hospital from January to December， 2019. They were grouped according to the random number table method， with 44 patients in each group. The control group was treated with conventional clopidogrel+Bayaspirin ......