急性肺损伤/急性呼吸窘迫综合征治疗进展
俞正秋 马春芳 蔡宛如[摘要] 急性肺损伤/急性呼吸窘迫综合征是临床常见的危重病症之一,起病急、发展快、病死率高,尽管在过去几年中,重症医学的发展使得ARDS的院内发生率和死亡率大幅下降,但目前临床上仍缺乏特效的治疗手段。肺保护通气、积极抗感染治疗和限制性液体管理是目前主要西医治疗策略,近年来有部分改进从而进一步降低该病的死亡率。此外,关于ARDS异质性的研究是近年来热点,期望找到可靠的生物标志物和适当的治疗靶点,更好地开展精准化治疗。随着医药治疗ARDS的实验和临床研究不断深入,中医药治疗ARDS也取得了一定的成果。本文回顾了近年来国内外相关文献,总结了中西医关于此病的最新研究治疗进展,以期为ALI/ARDS的临床个体化治疗和药物研发提供新思路。
[关键词] 急性肺损伤;急性呼吸窘迫综合征;间充质干细胞;中医药
[中图分类号] R563.8? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2021)13-0189-04
Advances in the treatment of acute lung injury/acute respiratory distress syndrome
YU Zhengqiu? ?MA Chunfang? ?CAI Wanru
The Second Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou? ?310053, China
[Abstract] Acute lung injury/acute respiratory distress syndrome is one of the common clinical critical illnesses. It has a rapid onset,rapid development,and high mortality rate. Although in the past few years, the development of intensive care medicine has led to a significant drop in the incidence and mortality of ARDS in the hospital. There is still a lack of clinically effective treatments. Lung-protective ventilation ......
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