张聪 戴钱姣 朱潇冉 潘颖璐 戴霞红

    [關键词] 肝衰竭;侵袭性肺感染;伏立康唑;卡泊芬净;安全性

    [中图分类号] R575.2? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)14-0115-04

    Comparison of efficacy of voriconazole and caspofungin in treatment of invasive lung infection complicated by liver failure

    ZHANG Cong1? ?DAI Qianjiao2? ?ZHU Xiaoran1? ?PAN Yinglu1? ?DAI Xiahong3

    1.Department of Pharmacy， Shulan(Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College， Hangzhou? ?310000， China; 2.Department of Hepatobiliary Surgery，the First Affiliated Hospital of Zhejiang University Medical College， Hangzhou? ?310000， China; 3.Department of Infectious Disease， Shulan (Hangzhou) Hospital Affiliated to Zhejiang Shuren University Shulan International Medical College， Hangzhou? ?310000， China

    [Abstract] Objective To explore the efficacy of voriconazole and caspofungin in the treatment of invasive lung infection complicated by liver failure. Methods A total of 78 patients with ACLF complicated with IPA who were treated with voriconazole and caspofungin in our hospital from January 2016 to June 2020 were collected as the research subjects. A total of 29 patients treated with voriconazole were included in the voriconazole group ......