蒋乐真 白光辉 刘锟 陈涛 臧依柔 严志汉

    [關键词] 生长激素缺乏症;特发性矮小;静息态功能磁共振;体素-镜像同伦连接

    [中图分类号] R725.8? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)16-0124-06

    The study of brain magnetic resonance mirror homotopy functional connection in children with growth hormone deficiency and idiopathic short stature

    JIANG Lezhen? ?BAI Guanghui? ?LIU Kun? ?CHEN Tao? ?ZANG Yirou? ?YAN Zhihan

    Department of Radiology and Imaging， the Second Affiliated Hospital of Wenzhou Medical University， Yuying Children′s Hospital， Wenzhou? ?325000， China

    [Abstract] Objective To study the functional connectivity changes between the two cerebral hemispheres in patients with growth hormone deficiency and short stature using resting-state functional magnetic resonance imaging (rs-fMRI) technology， and to analyze the correlation between changes in brain function and hormone and neuropsychological indicators. Methods A total of 26 children with growth hormone deficiency (GHD) and 44 children with idiopathic short stature (ISS) in the Department of Pediatric Endocrinology were enrolled in this study. A 3.0T MR resting-state brain functional magnetic resonance imaging sequence scan was performed on all children. At the same time ......