徐礼臻 徐旻 朱再生

    [关键词] 前列腺癌;PTEN 蛋白;Eg5 蛋白;免疫组织化学

    [中图分类号] R737.2? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2021)17-0004-04

    Expression and correlation of PTEN and Eg5 protein in prostate cancer

    XU Lizhen? ?XU Min? ?ZHU Zaisheng

    Department of Urology， Jinhua Hospital Affiliated to Zhejiang University Medical College， Jinhua? ?321000， China

    [Abstract] Objective To detect PTEN and Eg5 protein in prostate cancer(PC) by immunohistochemistry， and to explore the correlation between the expression of PTEN and Eg5 protein and clinicopathology of prostate cancer. Methods Immunohistochemical SP method was used to detect the expressions of PTEN and Eg5 protein in 81 PC cases and 45 cases with prostatic hyperplasia in Jinhua Hospital Affiliated to Zhejiang University School of Medicine from December 2014 to March 2016. The clinicopathological data of PC patients were analyzed with PTEN and Eg5 expression. Spearmen was used to analyze the correlation between PTEN and Eg5 protein expression. Results The positive rate of PTEN protein expression was 25.93% (21/81) in PC and 88.89% (40/45) in benign prostatic hyperplasia (BPH) ......