宁莉 王健 赵颖 姚琴 温华英

    [關键词] 缓解期;狼疮性肾炎;小剂量激素;羟氯喹;计划妊娠结局;肾脏损害

    [中图分类号] R692.3? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)18-0054-03

    Effects of low-dose hormone and hydroxychloroquine on planned pregnancy outcome and renal injury in patients with lupus nephritis in remission

    NING Li1? ?WANG Jian2? ?ZHAO Ying3? ?YAO Qin1? ?WEN Huaying1

    1.Department of Obstetrics and Gynecology， the First Affiliated Hospital of Gannan Medical University， Ganzhou 341000， China; 2.Department of Nephrology， the First Affiliated Hospital of Gannan Medical University， Ganzhou 341000， China; 3.Department of Reproductive Medicine， the First Affiliated Hospital of Gannan Medical University，Ganzhou? ?341000， China

    [Abstract] Objective To observe the influence of planned pregnancy on maternal safety and pregnancy outcome of patients with lupus nephritis (LN) in remission under the maintenance treatment of low-dose hormone and hydroxychloroquine， and to investigate the pregnancy time and drug use of LN patients. Methods A total of 23 patients with LN in remission were treated with low-dose prednisone (10 mg/day) and hydroxychloroquine (400 mg/ day) in our hospital from January 2013 to December 2018 ......