冯虹 秦国兴 陈晶

    [摘要] 目的 观察治疗性生活方式干预(TLC)对双相情感障碍患者糖脂代谢的影响。 方法 将80例双相情感障碍患者分为研究组与对照组，每组各40例，两组患者在入组后均接受12周的药物治疗。研究组采用治疗性生活方式干预，对照组采用常规健康宣教活动。观察12周，评定两组治疗前后的体重指数(BMI)、三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖水平。 结果 两组的BMI指数、空腹血糖、TC、TG、HDL-C、LDL-C比较，差异无统计学意义(P>0.05)。治疗12周后，研究组的BMI、空腹血糖、TG分别为(21.47±0.67)kg/m2、(4.87±0.36)mmol/L、(4.67±0.25)mmol/L，明顯低于对照组的(24.84±1.68)kg/m2、(6.23±0.28)mmol/L、(6.09±0.54)mmol/L，差异有统计学意义(P0.05)。 结论 基于治疗性生活方式干预可改善双相情感障碍患者糖脂代谢，值得临床应用。

    [关键词] 治疗性生活方式干预;双相情感障碍;糖代谢;脂代谢

    [中图分类号] R749? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2021)28-0088-04

    Clinical research on glucose and lipid metabolisms in patients with bipolar affective disorder based on therapeutic lifestyle changes

    FENG Hong? ?QIN Guoxing? ?CHEN Jing

    Department of Psychology，No.7 People′s Hospital of Shaoxing City in Zhejiang Province，Shaoxing? ?312000，China

    [Abstract] Objective To observe the impacts of therapeutic lifestyle changes(TLC) on glucose and lipid metabolisms in patients with bipolar affective disorder. Methods A total of 80 patients with bipolar affective disorder were divided into the study group (n=40) and the control group (n=40). Both groups were given drug treatment for 12 weeks after admitted to the group. The study group was intervened by TLC ......