陈莉 何春风

    [摘要] 目的 探討低能量平衡膳食联合运动干预对肥胖儿童脂质代谢和微炎症状态的影响。 方法 选取2018年1月至2020年6月丽水市人民医院门诊治疗肥胖患儿104例，随机分为干预组和对照组，每组各52例。对照组患儿予低能量平衡膳食，干预组患儿在对照组基础上加运动干预，两组患儿均干预8周。观察并比较两组患儿干预前和干预8周后脂质代谢及微炎症状态指标的变化。 结果 干预8周后，干预组和对照组患儿TC、TG和LDL-C水平明显下降(P<0.05)，且干预组患儿下降幅度更显著(P<0.05);同时干预组和对照组患儿血清hs-CRP和TNF-α水平明显下降(P<0.05)，且干预组患儿下降幅度更显著(P<0.05)。 结论 低能量平衡膳食联合运动干预用于肥胖儿童不仅可改善脂质代谢，有利于血脂达标，而且可降低血清炎症因子hs-CRP和TNF-α水平，改善微炎症状态。

    [关键词] 肥胖;儿童;低能量平衡膳食;运动干预;脂质代谢;微炎症状态

    [中图分类号] R723.1? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2022)02-0013-03

    Effect of low-energy balanced diet combined with exercise intervention on lipid metabolism and micro-inflammatory state in obese children

    CHEN Li1? ?HE Chunfeng2

    1.Department of Nutrition， Lishui People's Hospital in Zhejiang Province， Lishui? ?323000， China; 2.Department of Pediatrics， Lishui People's Hospital in Zhejiang Province， Lishui? ?323000， China

    [Abstract] Objective To explore the effect of low-energy balanced diet combined with exercise intervention on lipid metabolism and micro-inflammatory state in obese children. Methods A total of 104 patients with obesity treated in the outpatient department of Lishui People's Hospital from January 2018 to June 2020 were selected. They were randomly divided into the intervention group and the control group ......