周明强 余振华 张杰 侯雁云 赵志勇 谭秦湘

    [摘要] 目的 探讨高频超声、低频超声、FibroTouch、血清学检查四种无创性检查方法在评估慢性乙型肝炎肝纤维化程度中的价值。 方法 收集2019年1月至2021年1月在北京中医药大学深圳医院(龙岗)住院的慢性乙型肝炎患者132例，所有患者均行高频超声、低频超声、FibroTouch、血清学检查及超声引导下肝活检病理检查。记录高频超声总评分、低频超声总评分值、FibroTouch测量LSM、血清学检查计算APRI。以病理学检查为金标准，分析上述指标与肝纤维化分期相关性。结果 高频超声总评分值、LSM与肝纤维化分期呈高度正相关，相关系数为0.888、0.885;低频超声总评分值、APRI与肝纤维化分期呈中度正相关，相关系数为0.548、0.687。 结论 低频超声总评分值、APRI、高频超声总评分值、LSM对肝纤维化分期均有一定的诊断价值。高频超声总评分值、LSM诊断价值高于低频超声总评分值、APRI。

    [关键词] 高频超声;低频超声;FibroTouch;APRI;肝纤维化分期

    [中图分类号] R575.2? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2022)04-0127-04

    [Abstract] Objective To explore the value of four non-invasive methods of high-frequency ultrasound， low-frequency ultrasound， FibroTouch and serological examination in evaluating the degree of liver fibrosis induced by chronic hepatitis B. Methods A total of 132 patients with chronic hepatitis B who were hospitalized in Beijing University of Chinese Medicine Shenzhen Hospital(Longgang) from January 2019 to January 2021 were selected. All patients underwent high-frequency ultrasound ......