项挺 郑双

    [摘要] 目的 探讨整体营养状况主观评估(PGSGA)评分联合炎症因子对结直肠癌合并糖尿病术后感染的预测价值。方法 选择2020年1—12月台州市第一人民医院诊治的结直肠癌合并糖尿病患者88例，术后感染18例(感染组)、未感染70例(对照组)。比较两组PGSGA评分、可溶性髓系细胞触发受体1(sTREM-1)、C-反应蛋白(CRP)、血管内皮生长因子(VEGF)，多因素logistic回归分析术后感染危险因素，ROC曲线分析对结直肠癌合并糖尿病患者术后感染发生的预测价值。结果 sTREM-1≥209.68 μg/L、CRP>8.0 mg/L、VEGF≥174.55 pg/ml、PGSGA评分≥4.57分是结直肠癌合并糖尿病患者术后感染的独立危险因素(P<0.05)。sTREM-1、CRP、VEGF與PGSGA评分呈正相关(P<0.05);四者联合检测对术后感染的预测价值高于单独检测(P<0.05)。结论 PGSGA评分联合sTREM-1、CRP、VEGF可反映结直肠癌合并糖尿病术后是否发生感染，具有较高的预测准确性。

    [关键词] PGSGA评分;动态红细胞沉降率;C-反应蛋白;白细胞计数

    [中图分类号] R735.3? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2022)05-0004-04

    [Abstract] Objective To investigate the predictive value of the score of the Scored Patient Generated Subjective Global Assessment (PGSGA) combined with inflammatory factors for postoperative infection in colorectal cancer combined with diabetes mellitus. Methods A total of 88 patients with colorectal cancer combined with diabetes mellitus who were diagnosed and treated in Taizhou First People’s Hospital from January to December 2020 were selected as the study subjects ......