陈青华 石明晴 林群

    [摘要] 目的 探讨补肾疏肝方对非肥胖型多囊卵巢综合征(PCOS)(肾虚肝郁型)患者糖脂代谢、性激素的影响。方法 选择丽水市中医院2019年12月至2020年10月收治的非肥胖型PCOS(肾虚肝郁型)62例，采用抽签法分为对照组(n=31)与观察组(n=31)，对照组采用常规西药治疗，观察组采用补肾疏肝方治疗。观察治疗前后两组患者肾虚肝郁相关症状变化、实验室指标及证候疗效。结果 治疗前两组证候评分比较，差异无统计学意义(P>0.05)，治疗后两组证候评分低于治疗前，观察组低于对照组，差异有统计学意义(P<0.001);治疗前两组血清总胆固醇(TC)、甘油三酯(TG)、空腹血糖(FPG)、空腹胰岛素(FINS)、黄体生成素(LH)、卵泡刺激素(FSH)、游离睾酮(T)水平比较差异无统计学意义(P>0.05)，治疗后观察组FINS、LH水平低于对照组，差异有统计学意义(P<0.05)，观察组治疗后TC、FPG、FINS、LH、T水平低于治疗前，差异有统计学意义(P<0.05);观察组证候总有效率高于对照组，差异有统计学意义(P<0.05)。结论 补肾疏肝方治疗非肥胖型PCOS(肾虚肝郁型)效果肯定，可有效改善患者临床症状，降低糖脂代谢及性激素水平，值得临床应用与推广。

    [关键词] 补肾疏肝方;非肥胖型多囊卵巢综合征;肾虚肝郁;糖脂质代谢;性激素

    [中图分类号] R711.7? ? ? ? ? [文献标识码] A? ? ? ? ? [文章編号] 1673-9701(2022)05-0013-04

    [Abstract] Objective To investigate the effects of Bushen Shugan Formula on glucolipid metabolism and sex hormones in patients with non-obese polycystic ovary syndrome (PCOS) (kidney deficiency and liver depression type). Methods A total of 62 patients with non-obese PCOS (kidney deficiency and liver depression type) admitted to Lishui Hospital of Traditional Chinese Medicine from December 2019 to October 2020 were selected as the study subjects. They were divided into the control group (n=31) and the observation group (n=31) by the lottery method. The control group was treated with conventional western medicine ......