霍乐颍 黄辉文

    [摘要] 目的 分析新生儿败血症临床特征、病原菌分布情况，为临床诊治提供参考依据。方法 选取2015年1月至2020年12月珠海市妇幼保健院新生儿科病房收治的151例血培养证实为败血症患儿，按发病时间分为早发型败血症和晚发型败血症，对两组患儿的一般情况、临床表现、病原分布等进行统计分析。结果 早发型败血症以革兰阳性菌为主，其中无乳链球菌13株(26.53%)更为常见，晚发型败血症以革兰阴性菌为主，主要病原菌为肺炎克雷伯杆菌24株(23.50%)和大肠埃希菌29株(28.43%)。结论 在临床表征、高危因素及致病菌种类等方面，早发型败血症和晚发型败血症均存在差异，在临床诊疗中早期识别意义重大。

    [關键词] 新生儿;病原菌;败血症;早发型;晚发型

    [中图分类号] R725? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2022)05-0160-04

    [Abstract] Objective To analyze the clinical characteristics of neonatal sepsis and the distribution of pathogenic bacteria to provide reference for clinical diagnosis and treatment. Methods A total of 151 newborns with blood culture confirmed sepsis admitted to the Department of Neonatology of Zhuhai Center for Maternal and Child Health Care from January 2015 to December 2020 were selected. They were divided into the early-onset sepsis group and the late-onset sepsis group according to the time of onset. Statistical analyses on general conditions ......