倪丽 吴兆勇 毛书辉 陈校丹 李桂华 夏佳芸

    [摘要] 妊娠增加女性血栓栓塞的风险。低分子肝素作为一种抗凝药，随着其安全性和有效性被不断地证实，被越来越多地应用于临床妊娠期女性。本文以依诺肝素作为低分子肝素的代表，就低分子肝素与肝素的区别、低分子肝素在妊娠期的用法用量、适用人群、监测指标及紧急逆转进行讨论，为临床妊娠期女性正确使用低分子肝素提供参考依据。

    [关键词] 低分子肝素;妊娠期;肝素;依诺肝素

    [中图分类号] R711.6? ? ? ? ? [文献标识码] A? ? ? ? ? [文章编号] 1673-9701(2022)07-0189-04

    Advances in research on the use of low molecular heparin during pregnancy

    NI Li1? ?WU Zhaoyong1? ?MAO Shuhui2? ? CHEN Xiaodan3? ?LI Guihua2? ? XIA Jiayun1

    1.Department of Pharmacy，Affiliated Hospital of Jiaxing University，Jiaxing Maternal and Child Health Care Hospital in Zhejiang Province，Jiaxing? ?314000， China;2.Department of Obstetrics，Affiliated Hospital of Jiaxing University， Jiaxing Maternal and Child Health Care Hospital in Zhejiang Province， Jiaxing? ?314000， China;3.Department of Gynecology， Affiliated Hospital of Jiaxing University， Jiaxing Maternal and Child Health Care Hospital in Zhejiang Province，Jiaxing 314000， China

    [Abstract] Pregnancy increases the risk of thromboembolism in women. Low molecular heparin is increasingly being used as an anticoagulant in women during clinical pregnancy as its safety and efficacy continue to be proven.In this article ......