边灿军 吕钿 何杨伟 周黎琴 冯建钜

    [摘要] 目的 探讨补阳还五汤对气虚血瘀型大脑中动脉闭塞性脑梗死的疗效。 方法 随机选取浙江省诸暨市人民医院2019年1月至2020年6月收治的90例气虚血瘀型大脑中动脉闭塞性脑梗死患者，并按随机数字表法分为对照组与观察组，每组各45例。两组均采用常规西医治疗，观察组此基础上应用补阳还五汤，观察2周。比较两组治疗前后神经功能缺损评分(NIHSS)，D-二聚体(DD)，血小板聚集率(PAR)，血管性血友病因子(vWF)等指标及临床疗效。 结果 治疗1个疗程后，观察组总有效率为93.33%，显著高于对照组的80.00%，差异有统计学意义(P<0.05);观察组NIHSS评分、DD、PAR和vWF均明显低于对照组[分别为(6.12±1.94)分vs.(7.29±2.73)分，(0.47±0.12)mg/L vs.(0.61±0.19)mg/L，(57.63±8.60)% vs.(62.38±8.10)%，(108.48±20.39)% vs.(120.45±18.07)%，P<0.05]。 结论 补阳还五汤用于气虚血瘀型大脑中动脉闭塞性脑梗死的治疗有效，可改善患者脑血流动力学，促进其神经功能的恢复。

    [关键词] 急性脑梗死;补阳还五汤;血流动力学;神经功能缺损

    [中图分类号] R277.7? ? ? ? ? [文献标识码] B? ?; ? ? ? [文章编号] 1673-9701(2022)10-0155-04

    [Abstract] Objective To investigate the efficacy of Buyang Huanwu Decoction on middle cerebral artery occlusive cerebral infarction of Qi deficiency and blood stasis type. Methods A total of 90 patients with middle cerebral artery occlusive cerebral infarction of Qi deficiency and blood stasis type who were admitted to Zhejiang Zhuji People′s Hospital from January 2019 to June 2020 were selected. They were divided into a control group and an observation group according to the random number table ......