徐书蕾 顾方方 陶文霞

    [摘要] 目的 分析急性ST段抬高型心肌梗死(STEMI)患者直接PCI术后发生心力衰竭的独立危险因素。 方法? 选取2018年1月至2020年1月在湖州市中心医院心内科住院的STEMI患者160例，所有患者均行PCI术，根据Killip心功能进行分组，≥Ⅱ级为心力衰竭组80例，Ⅰ级为非心力衰竭组80例，收集两组患者临床病历资料，logistic回归分析STEMI患者PCI术后发生心力衰竭的独立危险因素;检测NT-proBNP、IL-32、MMP-9水平。结果高血压病史、糖尿病病史、血肌酐相对高值及血红蛋白相对低值为STEMI患者PCI术后发生心力衰竭的独立危险因素(P<0.05)。心力衰竭组患者血清NT-proBNP、IL-32及MMP-9水平明显高于非心力衰竭组，差异有统计学意义(P<0.05)。血清NT-proBNP、IL-32及MMP-9三指标联合检测价值较高。 结论? 高血压、糖尿病可能为STEMI直接PCI术后发生心力衰竭的危险因素，血清NT-proBNP、IL-32及MMP-9联合预测心力衰竭的价值较高。

    [关键词] 急性ST段抬高型心肌梗死;心力衰竭;危险因素;NT-proBNP;IL-32;MMP-9

    [中图分类号] R541.2? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2022)11-0052-04

    [Abstract] Objective To analyze the independent risk factors for heart failure in patients with acute ST-segment elevation myocardial infarction (STEMI) after direct percutaneous coronary intervention (PCI). Methods A total of 160 STEMI patients who were hospitalized in the Department of Cardiology of Huzhou Central Hospital from January 2018 to January 2020 were selected. All patients underwent PCI and were grouped according to Killip classification for cardiac function. 80 cases ≥ class Ⅱ were assigned as the heart failure group ......