ⅠA~ⅡA期宫颈癌盆腔淋巴结转移的高危因素
施姚 王兰英 汪棋秦 徐一腾 徐佳楠 黄春芳 张星光![](/images/paper/1673-9701/202213/17-1-l.jpg)
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[摘要] 目的 探讨ⅠA~ⅡA期宫颈癌盆腔淋巴结转移的高危因素。 方法 对浙江省余姚市人民医院2014年1月至2018年12月217例行开腹或腹腔镜下广泛子宫切除+盆腔淋巴结清扫术的ⅠA~ⅡA期宫颈癌患者的临床病理资料进行回顾性分析,运用多因素logistic回归分析研究发生盆腔淋巴结转移的高危因素。 结果 217例患者中,有44例盆腔淋巴结发生转移,转移率为20.3%,其中发生闭孔淋巴结转移最高,转移率为16.1%。χ2检验分析得出,宫颈癌临床分期、肿瘤大小、分化、宫颈间质浸润深度、脉管有无浸润及宫旁有无浸润与盆腔淋巴结转移相关(P<0.05)。多因素logistic回归分析显示,肿瘤分期Ⅱ期、肿瘤≥4 cm、宫颈间质浸润≥1/2、低分化、脉管阳性及宫旁浸润是盆腔淋巴结转移的独立危险因素(P<0.05)。 结论 肿瘤分期Ⅱ期、肿瘤≥4 cm、宫颈间质浸润≥1/2、低分化、脉管阳性及宫旁浸润容易发生盆腔淋巴结转移,建议系统性盆腔淋巴结清扫。
[关键词] 宫颈癌;盆腔淋巴结转移;高危因素;清扫
[中图分类号] R737.3? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2022)13-0063-03
[Abstract] Objective To investigate the high-risk factors for pelvic lymph node metastasis in patients with stage ⅠA-ⅡA cervical cancer. Methods The clinicopathological data of 217 patients with stage ⅠA-ⅡA cervical cancer who underwent laparotomy or laparoscopic extensive hysterectomy and pelvic lymph node dissection from January 2014 to December 2018 in Yuyao People′s hospital in Zhejiang Province were retrospectively analyzed. The high-risk factors for pelvic lymph node metastasis were analyzed by multivariate Logistic regression analysis. Results 44 of the 217 patients had pelvic lymph node metastasis ......
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