早期肠内营养支持对食管癌术后吻合口漏发生率及术后恢复的影响
李文辉 余欢明[摘要] 目的 本研究旨在比較食管癌根治术后早期肠内营养(EEN)和肠外营养(PN)对术后吻合口漏发生率及术后恢复的影响。方法? 纳入2016年7月~2020年7月在湖州师范学院附属第一医院行手术治疗的食管癌患者79例。根据营养支持方式分为早期肠内营养组(EEN组,n=39)和肠外营养组(PN组,n=40)。回顾性比较首次排便时间、术后输注白蛋白情况、住院时间、吻合口漏等并发症发生率、首次住院费用、围手术期病死率、营养支持相关并发症等。结果? 与PN组比较,EEN组住院时间明显缩短(P<0.05),首次住院费用明显降低(P<0.05),首次排便时间显著提前(P<0.05)。EEN组输注白蛋白剂量显著少于PN组(P<0.05)。EEN组术后吻合口漏发生率明显低于PN组(P<0.05)。EEN组术后高血糖发生率明显低于PN组(P<0.05)。结论? 食管癌根治术后48 h内早期开始EEN对减少术后吻合口漏发生率、促进早期恢复具有安全、经济的优势。
[关键词] 食管癌;肠内营养;吻合口漏;肠外营养
[中图分类号] R735.1? ? ? ? ? [文献标识码] B? ? ? ? ? [文章编号] 1673-9701(2022)17-0043-04
Effect of early enteral nutrition support on incidence of anastomotic leakage and postoperative recovery of esophageal cancer
LI Wenhui? ?YU Huanming
Department of Thoracic Surgery, First Affiliated Hospital of Huzhou University, Huzhou 313000, China
[Abstract] Objective To compare the effects of early enteral nutrition (EEN) and parenteral nutrition (PN) after radical resection of esophageal cancer on the incidence of postoperative anastomotic leakage and postoperative recovery. Methods A total of 79 patients with esophageal cancer underwent surgery in First Affiliated Hospital of Huzhou University from July 2016 to July 2020 were selected. They were divided into the early enteral nutrition group (the EEN group ......
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