岳弘伟 杨雪微 余丹华

    [摘要]?目的?探究三七通舒膠囊联合丁苯酞对急性脑梗死患者血液流变学、髓鞘碱性蛋白(myelin?basic?protein，MBP)、单核细胞趋化蛋白-1(monocyte?chemotactic?protein-1，MCP-1)及内皮素-1(endothelin-1，ET-1)的影响。方法?选取2021年1月至2022年4月于义乌市中心医院就诊的106例急性脑梗死患者，采用随机数字表法分为对照组(n=53)与观察组(n=53)。两组患者均给予常规对症支持治疗，对照组予以丁苯酞治疗，观察组在对照组基础上联合三七通舒胶囊治疗。观察两组治疗后临床疗效，比较两组治疗前后血液流变学、MBP、MCP-1、ET-1水平，以及美国国立卫生研究院卒中量表(National?Institutes?of?Health?stroke?scale，NIHSS)、改良Rankin量表(modified?Rankin?scale，mRS)分数及Barthel指数(Barthel?index，BI)。结果?治疗后，观察组临床总有效率显著高于对照组(P[Abstract]?Objective?To?investigate?the?effects?of?Sanqi?Tongshu?capsule?combined?with?butylphthalide?on?hemorheology，?myelin?basic?protein?(MBP)，?monocyte?chemotactic?protein-1?(MCP-1)?and?endothelin-1?(ET-1)?in?patients?with?acute?cerebral?infarction.?Methods?A?total?of?106?patients?with?acute?cerebral?infarction?attending?Yiwu?Central?Hospital?from?January?2021?to?April?2022?were?selected?and?divided?into?control?group?(n=53)?and?observation?group?(n=53)?according?to?the?random?number?table?method.?Patients?in?both?groups?were?given?conventional?symptomatic?support?treatment ......