王瑶 王灵俊 朱慧民

    [摘要]?目的?探究老年性骨質疏松(osteoporosis，OP)发病现状及老年性骨质疏松性骨折(osteoporosis?fracture，OF)发生的相关影响因素。方法?选取2019年1月至2022年1月于台州市中心医院老年科及骨科就诊的1000例老年患者临床资料进行回顾性分析，共检出OP患者310例，依据骨折与否分为OF组(n=100)和非OF组(n=210)，比较两组性别、年龄、既往有无骨折史、不同部位骨密度(bone?mineral?density，BMD)，以及Ⅰ型胶原羧基端肽β特殊序列(β?C-terminal?cross-linked?telopeptides?of?type?Ⅰ?collagen，β-CTX)、25羟维生素D3[25?hydroxyvitamin?D3，25-(OH)D3]、Ⅰ型前胶原氨基端延长肽(propeptide?of?type?Ⅰ?procollagen，PINP)等骨代谢指标，采用多因素Logistic回归分析老年OF发生的危险因素；采用受试者操作特征(receiver?operator?characteristics，ROC)曲线分析血清骨代谢指标对OF的预测价值。结果?1000例老年患者中检出OP患者310例，其中OF患者为100例。OF组股骨大转子、股骨转子间、总髋部、Ward三角区的BMD均显著小于非OF组(P[Abstract]?Objective?To?explore?the?prevalence?of?osteoporosis?(OP)?in?the?elderly?and?related?influencing?factors?of?osteoporosis?fracture?(OF)?in?the?elderly.?Methods?A?total?of?1000?elderly?patients?attending?the?geriatric?and?orthopaedic?departments?of?Taizhou?Central?Hospital?from?January?2019?to?January?2022?were?selected?for?retrospective?analysis?of?clinical?data.?A?total?of?310?patients?with?OP?were?detected?and?divided?into?OF?group?(n=100)?and?non-OF?group?(n=210)?based?on?whether?a?fracture?or?not.?Gender ......