吕燕妮 付龙生 胥甜甜 周芸 赖敏芳 宋小玲 陈瑾

    [摘要]?目的?本研究旨在評估发生医院获得性感染(hospital-acquired?infection，HAI)的风险因素及其对患者预后的影响。方法?回顾性分析南昌大学第一附属医院2019年1月至2021年12月入院接受康复治疗的脑损伤患者401例，分为HAI组和无感染组，单因素和多因素分析对比两组患者的特征信息，分析HAI的风险因素，并以患者住院时间、神经功能和生活指数为指标，评价HAI对患者预后的影响。结果?HAI者53例，平均年龄(56.68±16.29)岁，无感染者348例，平均年龄(48.06±16.19)岁。单因素回归分析后提示年龄>65岁、男性、心脏疾病、肾功能不全、糖尿病、气管切开、机械通气、抗菌药物治疗在HAI组和无感染组间差异有统计学意义(P65岁、气管切开、机械通气是HAI的风险因素。HAI组患者住院时间比无感染组略长，但差异无统计学意义(P>0.05)。HAI组神经功能损害、汉密尔顿抑郁量表(Hamilton?depression?scale，HAMD)、改良Rankin量表(modified?Rankin?scale，mRS)评分高于无感染组，差异有统计学意义(P

    [Abstract]?Objective?Patients?with?brain?injury?are?often?hospitalized?for?rehabilitation?treatment，?but?there?exists?a?risk?of?hospital-acquired?infection?(HAI).?The?research?aims?to?evaluate?the?risk?factors?of?hospital?acquired?infection?and?its?impact?on?the?prognosis?of?patients.?Methods?A?retrospective?analysis?was?performed?on?401?patients?with?brain?injury?who?were?hospitalized?for?rehabilitation?treatment?from?January?2019?to?December?2021?in?the?First?Affiliated?Hospital?of?Nanchang?University.?The?patients?were?divided?into?two?groups：?HAI?group?and?non-infected?group.?The?characteristics?of?the?two?groups?were?compared?by?univariate?and?multivariate?analysis ......